Nuisance compounds in cellular assays

Compounds that exhibit assay interference or undesirable mechanisms of bioactivity (“nuisance compounds”) are routinely encountered in cellular assays, including phenotypic and high-content screening assays. Much is known regarding compound-dependent assay interferences in cell-free assays. However,...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Dahlin, Jayme L, Auld, Douglas S, Rothenaigner, Ina, Haney, Steve, Sexton, Jonathan Z, Nissink, J Willem M, Walsh, Jarrod, Lee, Jonathan A, Strelow, John M, Willard, Francis S, Ferrins, Lori, Baell, Jonathan B, Walters, Michael A, Hua, Bruce K, Hadian, Kamyar, Wagner, Bridget K
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979533/
https://ncbi.nlm.nih.gov/pubmed/33592188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2021.01.021
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