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Brief Guide: Experimental Strategies for High-Quality Hit Selection from Small-Molecule Screening Campaigns
Small-molecule screening is a powerful approach to identify modulators of either specific biological targets or cellular pathways with phenotypic endpoints. A myriad of assay technologies are available to assess the activity of enzymes, monitor protein–protein interactions, measure transcription fac...
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| Опубликовано в: : | SLAS Discov |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
SAGE Publications
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8293735/ https://ncbi.nlm.nih.gov/pubmed/33882754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/24725552211008862 |
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