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Identification of Small-Molecule Frequent Hitters from AlphaScreen High-Throughput Screens
Although small-molecule drug discovery efforts have focused largely on enzyme, receptor, and ion-channel targets, there has been an increase in such activities to search for protein-protein interaction (PPI) disruptors by applying high-throughout screening (HTS)–compatible protein-binding assays. Ho...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153540/ https://ncbi.nlm.nih.gov/pubmed/24371213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113516861 |
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