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An in vivo high-throughput screening for riboswitch ligands using a reverse reporter gene system
Riboswitches are bacterial RNA elements that regulate gene expression in response to metabolite or ion abundance and are considered as potential drug targets. In recent years a number of methods to find non-natural riboswitch ligands have been described. Here we report a high-throughput in vivo scre...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552694/ https://ncbi.nlm.nih.gov/pubmed/28798404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07870-w |
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