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A High Throughput Screen for Synthetic Riboswitches Reveals Mechanistic Insights into their Function
Riboswitches are RNA-based genetic control elements that regulate gene expression in a ligand-dependent fashion without the need for proteins. The ability to create synthetic riboswitches that control gene expression in response to any desired small-molecule ligand will enable the development of sen...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1858662/ https://ncbi.nlm.nih.gov/pubmed/17317571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2006.12.008 |
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