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High-throughput in vivo vertebrate screening

We demonstrate a high-throughput platform for cellular-resolution in vivo pharmaceutical and genetic screens on zebrafish larvae. The system automatically loads animals from reservoirs or multiwell plates, and positions and orients them for high-speed confocal imaging and laser manipulation of both...

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Detalhes bibliográficos
Main Authors: Pardo-Martin, Carlos, Chang, Tsung-Yao, Koo, Bryan Kyo, Gilleland, Cody L., Wasserman, Steven C., Yanik, Mehmet Fatih
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941625/
https://ncbi.nlm.nih.gov/pubmed/20639868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1481
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