Identification of Small-Molecule Frequent Hitters from AlphaScreen High-Throughput Screens

Although small-molecule drug discovery efforts have focused largely on enzyme, receptor, and ion-channel targets, there has been an increase in such activities to search for protein-protein interaction (PPI) disruptors by applying high-throughout screening (HTS)–compatible protein-binding assays. Ho...

Full description

Saved in:
Bibliographic Details
Main Authors: Schorpp, Kenji, Rothenaigner, Ina, Salmina, Elena, Reinshagen, Jeanette, Low, Terence, Brenke, Jara K., Gopalakrishnan, Jay, Tetko, Igor V., Gul, Sheraz, Hadian, Kamyar
Format: Artigo
Language:Inglês
Published: SAGE Publications 2014
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153540/
https://ncbi.nlm.nih.gov/pubmed/24371213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113516861
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items