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Identification of Anti-prion Compounds using a Novel Cellular Assay
Prion diseases are devastating neurodegenerative disorders with no known cure. One strategy for developing therapies for these diseases is to identify compounds that block conversion of the cellular form of the prion protein (PrP(C)) into the infectious isoform (PrP(Sc)). Most previous efforts to di...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5207084/ https://ncbi.nlm.nih.gov/pubmed/27803163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745612 |
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