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A Photochemical Flow Reactor for Large Scale Syntheses of Aglain and Rocaglate Natural Product Analogs

Herein, we report the development of continuous flow photoreactors for large scale ESIPT-mediated [3+2]-photocycloaddition of 2-(p-methoxyphenyl)-3-hydroxyflavone and cinnamate- derived dipolarophiles. These reactors can be efficiently numbered up to increase throughput two orders of magnitude great...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Yueh, Han, Gao, Qiwen, Porco, John A., Beeler, Aaron B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696104/
https://ncbi.nlm.nih.gov/pubmed/28666859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.06.010
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