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High-Throughput 1,536-Well Fluorescence Polarization Assays for α(1)-Acid Glycoprotein and Human Serum Albumin Binding
Two major plasma proteins in humans are primarily responsible for drug binding, the α(1)-acid-glycoprotein (AGP) and human serum albumin (HSA). The availability of at least a semiquantitative high-throughput assay for assessment of protein binding is expected to aid in bridging the current gap betwe...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3447978/ https://ncbi.nlm.nih.gov/pubmed/23029124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045594 |
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