A 1,536-Well-Based Kinetic HTS Assay for Inhibitors of Schistosoma mansoni Thioredoxin Glutathione Reductase

Schistosomiasis is a major neglected tropical disease that currently affects over 200 million people and leads to over 200,000 annual deaths. Schistosoma mansoni parasites survive in humans in part because of a set of antioxidant enzymes that continuously degrade reactive oxygen species produced by...

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Autori principali: Lea, Wendy A., Jadhav, Ajit, Rai, Ganesha, Sayed, Ahmed A., Cass, Cynthia L., Inglese, James, Williams, David L., Austin, Christopher P., Simeonov, Anton
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2008
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669305/
https://ncbi.nlm.nih.gov/pubmed/18665782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2008.149
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