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Investigations on the Catalytic Mechanism of Thioredoxin Glutathione Reductase (TGR) from Schistosoma mansoni

Thioredoxin glutathione reductase from Schistosoma mansoni (SmTGR) catalyzes the reduction of both thioredoxin and glutathione disulfides (GSSG), thus playing a crucial role in maintaining redox homeostasis in the parasite. In line with this role, previous studies have demonstrated that SmTGR is a p...

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Autores principales: Huang, Hsin-Hung, Day, Latasha, Cass, Cynthia L., Ballou, David P., Williams, Charles H., Williams, David L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658134/
https://ncbi.nlm.nih.gov/pubmed/21630672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200107n
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