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Investigations on the Catalytic Mechanism of Thioredoxin Glutathione Reductase (TGR) from Schistosoma mansoni

Thioredoxin glutathione reductase from Schistosoma mansoni (SmTGR) catalyzes the reduction of both thioredoxin and glutathione disulfides (GSSG), thus playing a crucial role in maintaining redox homeostasis in the parasite. In line with this role, previous studies have demonstrated that SmTGR is a p...

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Detalhes bibliográficos
Main Authors: Huang, Hsin-Hung, Day, Latasha, Cass, Cynthia L., Ballou, David P., Williams, Charles H., Williams, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658134/
https://ncbi.nlm.nih.gov/pubmed/21630672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200107n
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