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AlphaScreen-Based Assays: Ultra-High-Throughput Screening for Small-Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions

AlphaScreen technology has been routinely utilized in high throughput screening assays to quantify analyte accumulation or depletion, bimolecular interactions, and post-translational modifications. The high signal-to-background, dynamic range and sensitivity associated with AlphaScreens as well as t...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Yasgar, Adam, Jadhav, Ajit, Simeonov, Anton, Coussens, Nathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444910/
https://ncbi.nlm.nih.gov/pubmed/27316989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3673-1_5
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