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AlphaScreen-Based Assays: Ultra-High-Throughput Screening for Small-Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions
AlphaScreen technology has been routinely utilized in high throughput screening assays to quantify analyte accumulation or depletion, bimolecular interactions, and post-translational modifications. The high signal-to-background, dynamic range and sensitivity associated with AlphaScreens as well as t...
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Publicado no: | Methods Mol Biol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5444910/ https://ncbi.nlm.nih.gov/pubmed/27316989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3673-1_5 |
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