A carregar...

A parallel chemistry approach to identify novel nuclear receptor ligands based on the GW0742 scaffold

We describe the parallel synthesis of novel analogs of GW0742, a peroxisome proliferator-activated receptor δ (PPARδ) agonist. For that purpose, modified reaction conditions were applied, such as a solid-phase palladium-catalyzed Suzuki coupling. In addition, tetrazole-based compounds were generated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Comb Sci
Main Authors: Teske, Kelly A., Rai, Ganesha, Nandhikonda, Premchendar, Sidhu, Preetpal S., Feleke, Belaynesh, Simeonov, Anton, Yasgar, Adam, Jadhav, Ajit, Maloney, David J., Arnold, Leggy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643073/
https://ncbi.nlm.nih.gov/pubmed/28825467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.7b00066
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!