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A parallel chemistry approach to identify novel nuclear receptor ligands based on the GW0742 scaffold
We describe the parallel synthesis of novel analogs of GW0742, a peroxisome proliferator-activated receptor δ (PPARδ) agonist. For that purpose, modified reaction conditions were applied, such as a solid-phase palladium-catalyzed Suzuki coupling. In addition, tetrazole-based compounds were generated...
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| Vydáno v: | ACS Comb Sci |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5643073/ https://ncbi.nlm.nih.gov/pubmed/28825467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.7b00066 |
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