Development of Novel Vitamin D Receptor–Coactivator Inhibitors

[Image: see text] Nuclear receptor coregulators are master regulators of transcription and selectively interact with the vitamin D receptor (VDR) to modulate cell differentiation, cell proliferation, and calcium homeostasis. Herein, we report the syntheses and evaluation of highly potent and selecti...

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Hauptverfasser: Sidhu, Preetpal S., Nassif, Nicholas, McCallum, Megan M., Teske, Kelly, Feleke, Belaynesh, Yuan, Nina Y., Nandhikonda, Premchendar, Cook, James M., Singh, Rakesh K., Bikle, Daniel D., Arnold, Leggy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007349/
https://ncbi.nlm.nih.gov/pubmed/24799995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400462j
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