IDENTIFICATION OF VDR ANTAGONISTS AMONG NUCLEAR RECEPTOR LIGANDS USING VIRTUAL SCREENING

Herein, we described the development of two virtual screens to identify new vitamin D receptor (VDR) antagonists among nuclear receptor (NR) ligands. Therefore, a database of 14330 nuclear receptor ligands and their NR affinities was assembled using the online available “Binding Database”. Two diffe...

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Detalhes bibliográficos
Publicado no:Nucl Receptor Res
Main Authors: Teske, Kelly, Nandhikonda, Premchendar, Bogart, Jonathan W., Feleke, Belaynesh, Sidhu, Preetpal, Yuan, Nina, Preston, Joshua, Goy, Robin, Han, Lanlan, Silvaggi, Nicholas R, Singh, Rakesh K., Bikle, Daniel D., Cook, James M., Arnold, Leggy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240308/
https://ncbi.nlm.nih.gov/pubmed/25419525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11131/2014/101076
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