Discovery of the First Irreversible Small Molecule Inhibitors of the Interaction between the Vitamin D Receptor and Coactivators

The vitamin D receptor (VDR) is a nuclear hormone receptor that regulates cell proliferation, cell differentiation, and calcium homeostasis. The receptor is activated by vitamin D analogs that induce the disruption of VDR-corepressor binding and promote VDR-coactivator interactions. The interactions...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Nandhikonda, Premchendar, Lynt, Wen Z., McCallum, Megan M., Ara, Tahniyath, Baranowski, Athena M., Yuan, Nina Y., Pearson, Dana, Bikle, Daniel D., Guy, R. Kiplin, Arnold, Leggy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364162/
https://ncbi.nlm.nih.gov/pubmed/22563729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300460c
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados