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A Strategy to Discover Inhibitors of Bacillus subtilis Surfactin-type Phosphopantetheinyl Transferase

Surfactin-type phosphopantetheinyl transferases (Sfp-PPTases) are responsible for modifying type I polyketide and nonribosomal peptide synthases of prokaryotes and have been implicated in the activation of a variety of pathogen-associated virulence factors. As such, inhibitors of this enzyme class r...

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Bibliografiska uppgifter
Huvudupphovsmän: Yasgar, Adam, Foley, Timothy, Jadhav, Ajit, Inglese, James, Burkart, Michael, Simeonov, Anton
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992954/
https://ncbi.nlm.nih.gov/pubmed/20094656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b913291k
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