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Fluorescent techniques for discovery and characterization of phosphopantetheinyl transferase inhibitors

Phosphopantetheinyl transferase (E.C. 2.7.8.-) activates biosynthetic pathways that synthesize both primary and secondary metabolites in bacteria. Inhibitors of these enzymes have the potential to serve as antibiotic compounds that function through a unique mode of action and possess clinical utilit...

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Detalhes bibliográficos
Publicado no:J Antibiot (Tokyo)
Main Authors: Kosa, Nicolas M., Foley, Timothy L., Burkart, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807864/
https://ncbi.nlm.nih.gov/pubmed/24192555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2013.106
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