Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential

Nuclear receptors, such as the retinoid X receptor (RXR), are proteins that regulate a myriad of cellular processes. Molecules that function as RXR agonists are of special interest for the prevention and control of carcinogenesis. The majority of these ligands possess an acidic moiety that is believ...

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Detalhes bibliográficos
Main Authors: Conda-Sheridan, Martin, Park, Eun-Jung, Beck, Daniel E., Narasimha Reddy, P. V., Nguyen, Trung X., Hu, Bingjie, Chen, Lian, White, Jerry J., van Breemen, Richard B., Pezzuto, John M., Cushman, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623729/
https://ncbi.nlm.nih.gov/pubmed/23472886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400026k
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