Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential

Nuclear receptors, such as the retinoid X receptor (RXR), are proteins that regulate a myriad of cellular processes. Molecules that function as RXR agonists are of special interest for the prevention and control of carcinogenesis. The majority of these ligands possess an acidic moiety that is believ...

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Main Authors: Conda-Sheridan, Martin, Park, Eun-Jung, Beck, Daniel E., Narasimha Reddy, P. V., Nguyen, Trung X., Hu, Bingjie, Chen, Lian, White, Jerry J., van Breemen, Richard B., Pezzuto, John M., Cushman, Mark
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623729/
https://ncbi.nlm.nih.gov/pubmed/23472886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400026k
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