Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential

Nuclear receptors, such as the retinoid X receptor (RXR), are proteins that regulate a myriad of cellular processes. Molecules that function as RXR agonists are of special interest for the prevention and control of carcinogenesis. The majority of these ligands possess an acidic moiety that is believ...

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Hlavní autoři: Conda-Sheridan, Martin, Park, Eun-Jung, Beck, Daniel E., Narasimha Reddy, P. V., Nguyen, Trung X., Hu, Bingjie, Chen, Lian, White, Jerry J., van Breemen, Richard B., Pezzuto, John M., Cushman, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623729/
https://ncbi.nlm.nih.gov/pubmed/23472886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400026k
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