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Induction of retinoid X receptor activity and consequent up-regulation of p21(WAF1/CIP1) by indenoisoquinolines in MCF7 cells
Retinoid X receptor (RXR) has been targeted for the chemoprevention and treatment of cancer. To discover potential agents acting through RXRs, we utilized an RXR response element-luciferase reporter gene assay. Following extensive screening, 3-amino-6-(3-aminopropyl)-5,6-dihydro-5,11-dioxo-11H-inden...
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| Опубликовано в: : | Cancer Prev Res (Phila) |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554444/ https://ncbi.nlm.nih.gov/pubmed/21464033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0004 |
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