Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids

The mechanisms by which retinoids regulate initiation of mRNA translation for proteins that mediate their biological effects are not known. We have previously shown that all-trans-retinoic acid (ATRA) induces mTOR-mediated activation of the p70 S6 kinase, suggesting the existence of a mechanism by w...

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Bibliografiske detaljer
Main Authors: Kannan-Thulasiraman, Padma, Dolniak, Blazej, Kaur, Surinder, Sassano, Antonella, Kalvakolanu, Dhananjaya V., Hay, Nissim, Platanias, Leonidas C.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390818/
https://ncbi.nlm.nih.gov/pubmed/18280804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.02.028
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