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The DEAD-box RNA helicase DDX41 is a novel repressor of p21(WAF1/CIP1) mRNA translation

The cyclin-dependent kinase inhibitor p21 is an important player in stress pathways exhibiting both tumor-suppressive and oncogenic functions. Thus, expression of p21 has to be tightly controlled, which is achieved by numerous mechanisms at the transcriptional, translational, and posttranslational l...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Peters, Dominik, Radine, Claudia, Reese, Alina, Budach, Wilfried, Sohn, Dennis, Jänicke, Reiner U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437239/
https://ncbi.nlm.nih.gov/pubmed/28348086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.772327
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