The DEAD-box RNA helicase DDX41 is a novel repressor of p21(WAF1/CIP1) mRNA translation

The cyclin-dependent kinase inhibitor p21 is an important player in stress pathways exhibiting both tumor-suppressive and oncogenic functions. Thus, expression of p21 has to be tightly controlled, which is achieved by numerous mechanisms at the transcriptional, translational, and posttranslational l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Peters, Dominik, Radine, Claudia, Reese, Alina, Budach, Wilfried, Sohn, Dennis, Jänicke, Reiner U.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437239/
https://ncbi.nlm.nih.gov/pubmed/28348086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.772327
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