Modulation of Chemokines and Allergic Airway Inflammation by Selective Local Sphingosine-1-phosphate Receptor 1 Agonism in Lungs

Por Marsolais, David, Yagi, Saiko, Kago, Tomoyuki, Leaf, Nora, Rosen, Hugh
Publicado em 2011

S1P(1) Receptor Modulation with Cyclical Recovery from Lymphopenia Ameliorates Mouse Model of Multiple Sclerosis

Por Gonzalez-Cabrera, Pedro J., Cahalan, Stuart M., Nguyen, Nhan, Sarkisyan, Gor, Leaf, Nora B., Cameron, Michael D., Kago, Tomoyuki, Rosen, Hugh
Publicado em 2012

S1PR1-mediated IFNAR1 degradation modulates plasmacytoid dendritic cell interferon-α autoamplification

Por Teijaro, John R., Studer, Sean, Leaf, Nora, Kiosses, William B., Nguyen, Nhan, Matsuki, Kosuke, Negishi, Hideo, Taniguchi, Tadatsugu, Oldstone, Michael B. A., Rosen, Hugh
Publicado no Proc Natl Acad Sci U S A (2016)

Sphingosine 1-Phosphate Receptor 1 (S1P(1)) Upregulation and Amelioration of Experimental Autoimmune Encephalomyelitis by an S1P(1) Antagonist

Por Cahalan, Stuart M., Gonzalez-Cabrera, Pedro J., Nguyen, Nhan, Guerrero, Miguel, Cisar, Elizabeth A. George, Leaf, Nora B., Brown, Steven J., Roberts, Edward, Rosen, Hugh
Publicado em 2013

Full pharmacological efficacy of a novel S1P(1) agonist that does not require S1P-like head-group interactions

Por Gonzalez-Cabrera, Pedro J., Jo, Euijung, Sanna, M. Germana, Brown, Steven, Leaf, Nora, Marsolais, David, Schaeffer, Marie-Therese, Chapman, Jacqueline, Cameron, Michael, Guerrero, Miguel, Roberts, Edward, Rosen, Hugh
Publicado em 2008

Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)

Por Guerrero, Miguel, Urbano, Mariangela, Kim, Eun-Kyong, Gamo, Ana M., Riley, Sean, Abgaryan, Lusine, Leaf, Nora, Van Orden, Lori Jean, Brown, Steven J., Xie, Jennifer Y., Porreca, Frank, Cameron, Michael D., Rosen, Hugh, Roberts, Edward
Publicado no J Med Chem (2019)

Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Cond...

Por Sanna, M. Germana, Vincent, Kevin P., Repetto, Emanuela, Nguyen, Nhan, Brown, Steven J., Abgaryan, Lusine, Riley, Sean W., Leaf, Nora B., Cahalan, Stuart M., Kiosses, William B., Kohno, Yasushi, Brown, Joan Heller, McCulloch, Andrew D., Rosen, Hugh, Gonzalez-Cabrera, Pedro J.
Publicado no Mol Pharmacol (2016)