Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction

The molecular pharmacology of the G protein–coupled receptors for sphingosine 1-phosphate (S1P) provides important insight into established and new therapeutic targets. A new, potent bitopic S1P(3) antagonist, SPM-354, with in vivo activity, has been used, together with S1P(3)-knockin and S1P(3)-kno...

全面介紹

Na minha lista:
書目詳細資料
發表在:Mol Pharmacol
Main Authors: Sanna, M. Germana, Vincent, Kevin P., Repetto, Emanuela, Nguyen, Nhan, Brown, Steven J., Abgaryan, Lusine, Riley, Sean W., Leaf, Nora B., Cahalan, Stuart M., Kiosses, William B., Kohno, Yasushi, Brown, Joan Heller, McCulloch, Andrew D., Rosen, Hugh, Gonzalez-Cabrera, Pedro J.
格式: Artigo
語言:Inglês
出版: The American Society for Pharmacology and Experimental Therapeutics 2016
主題:
Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702096/
https://ncbi.nlm.nih.gov/pubmed/26494861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.100222
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍