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S1P(3) receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF

Pulmonary pathologies including adult respiratory distress syndrome are characterized by disruption of pulmonary integrity and edema compromising respiratory function. Sphingosine 1-phosphate (S1P) is a lipid mediator synthesized and/or stored in mast cells, platelets, and epithelial cells, with pro...

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Detalhes bibliográficos
Main Authors: Gon, Yasuhiro, Wood, Malcolm R., Kiosses, William B., Jo, Euijung, Sanna, M. Germana, Chun, Jerold, Rosen, Hugh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166603/
https://ncbi.nlm.nih.gov/pubmed/15968000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501997102
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