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S1P(3) receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF
Pulmonary pathologies including adult respiratory distress syndrome are characterized by disruption of pulmonary integrity and edema compromising respiratory function. Sphingosine 1-phosphate (S1P) is a lipid mediator synthesized and/or stored in mast cells, platelets, and epithelial cells, with pro...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1166603/ https://ncbi.nlm.nih.gov/pubmed/15968000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501997102 |
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