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Modulation of Chemokines and Allergic Airway Inflammation by Selective Local Sphingosine-1-phosphate Receptor 1 Agonism in Lungs

Sphingosine-1-phosphate and its receptors have emerged as important modulators of the immune response. The sphingosine-1-phosphate prodrug 2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol (FTY720) can alleviate experimental allergic airway inflammation. Nevertheless, the role of individual sphingo...

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Detalhes bibliográficos
Main Authors: Marsolais, David, Yagi, Saiko, Kago, Tomoyuki, Leaf, Nora, Rosen, Hugh
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014274/
https://ncbi.nlm.nih.gov/pubmed/20935081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.066811
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