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Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules

Biological barriers regulate the passage of cells, pathogens, fluids, nutrients, ions and signalling molecules between anatomical compartments during homeostasis and disease. Yet strategies that allow for reversible therapeutic modulation of these barriers are still in their infancy. The enhancement...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Marsolais, David, Rosen, Hugh
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455967/
https://ncbi.nlm.nih.gov/pubmed/19300460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2356
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