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Sphingosine 1-Phosphate Receptor Modulators and Drug Discovery

Initial discovery on sphingosine 1-phosphate (S1P) as an intracellular second messenger was faced unexpectedly with roles of S1P as a first messenger, which subsequently resulted in cloning of its G protein-coupled receptors, S1P(1–5). The molecular identification of S1P receptors opened up a new av...

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Vydáno v:Biomol Ther (Seoul)
Hlavní autoři: Park, Soo-Jin, Im, Dong-Soon
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Applied Pharmacology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207465/
https://ncbi.nlm.nih.gov/pubmed/28035084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.160
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