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Blockage of sphingosine‐1‐phosphate receptor 2 attenuates allergic asthma in mice

BACKGROUND AND PURPOSE: Sphingosine‐1‐phosphate 2 (S1P(2)) receptors have been implicated in degranulation of mast cells. However, functions of S1P(2) receptors have not been investigated in an in vivo model of allergic asthma. EXPERIMENTAL APPROACH: Using an ovalbumin (OVA)‐induced asthma model, th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Park, Soo‐Jin, Im, Dong‐Soon
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433643/
https://ncbi.nlm.nih.gov/pubmed/30706444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14597
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