One-Year Routine Opportunistic Screening for Hypertension in Formal Medical Settings and Potential Improvements in Hypertension Awareness Among Older Persons in Developing Countrie...

Por Maurer, Jürgen, Ramos, Alejandra
Publicado no Am J Epidemiol (2015)

Intrinsic Obstacles to Human Immunodeficiency Virus Type 1 Coreceptor Switching

Por Pastore, Cristina, Ramos, Alejandra, Mosier, Donald E.
Publicado em 2004

Evolution of CXCR4-Using Human Immunodeficiency Virus Type 1 SF162 Is Associated with Two Unique Envelope Mutations

Por Kiselyeva, Yana, Nedellec, Rebecca, Ramos, Alejandra, Pastore, Cristina, Margolis, Leonid B., Mosier, Donald E.
Publicado em 2007

Conserved Changes in Envelope Function during Human Immunodeficiency Virus Type 1 Coreceptor Switching

Por Pastore, Cristina, Nedellec, Rebecca, Ramos, Alejandra, Hartley, Oliver, Miamidian, John L., Reeves, Jacqueline D., Mosier, Donald E.
Publicado em 2007

Medicinal chemistry applied to a synthetic protein: Development of highly potent HIV entry inhibitors

Por Hartley, Oliver, Gaertner, Hubert, Wilken, Jill, Thompson, Darren, Fish, Richard, Ramos, Alejandra, Pastore, Cristina, Dufour, Brigitte, Cerini, Fabrice, Melotti, Astrid, Heveker, Nikolaus, Picard, Laurent, Alizon, Marc, Mosier, Donald, Kent, Stephen, Offord, Robin
Publicado em 2004

PGV04, an HIV-1 gp120 CD4 Binding Site Antibody, Is Broad and Potent in Neutralization but Does Not Induce Conformational Changes Characteristic of CD4

Por Falkowska, Emilia, Ramos, Alejandra, Feng, Yu, Zhou, Tongqing, Moquin, Stephanie, Walker, Laura M., Wu, Xueling, Seaman, Michael S., Wrin, Terri, Kwong, Peter D., Wyatt, Richard T., Mascola, John R., Poignard, Pascal, Burton, Dennis R.
Publicado em 2012

Rapid development of glycan-specific, broad, and potent anti–HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

Por Walker, Laura M., Sok, Devin, Nishimura, Yoshiaki, Donau, Olivia, Sadjadpour, Reza, Gautam, Rajeev, Shingai, Masashi, Pejchal, Robert, Ramos, Alejandra, Simek, Melissa D., Geng, Yu, Wilson, Ian A., Poignard, Pascal, Martin, Malcolm A., Burton, Dennis R.
Publicado em 2011

Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV

Por Sok, Devin, Doores, Katie J., Briney, Bryan, Le, Khoa M., Saye-Francisco, Karen F., Ramos, Alejandra, Kulp, Daniel W., Julien, Jean-Philippe, Menis, Sergey, Wickramasinghe, Lalinda, Seaman, Michael S., Schief, William R., Wilson, Ian A., Poignard, Pascal, Burton, Dennis R.
Publicado em 2014

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch

Por MacLeod, Daniel T., Choi, Nancy M., Briney, Bryan, Garces, Fernando, Ver, Lorena S., Landais, Elise, Murrell, Ben, Wrin, Terri, Kilembe, William, Liang, Chi-Hui, Ramos, Alejandra, Bian, Chaoran B., Wickramasinghe, Lalinda, Kong, Leopold, Eren, Kemal, Wu, Chung-Yi, Wong, Chi-Huey, Kosakovsky Pond, Sergei L., Wilson, Ian A., Burton, Dennis R., Poignard, Pascal
Publicado no Immunity (2016)

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike

Por Lee, Jeong Hyun, Leaman, Daniel P., Kim, Arthur S., Torrents de la Peña, Alba, Sliepen, Kwinten, Yasmeen, Anila, Derking, Ronald, Ramos, Alejandra, de Taeye, Steven W., Ozorowski, Gabriel, Klein, Florian, Burton, Dennis R., Nussenzweig, Michel C., Poignard, Pascal, Moore, John P., Klasse, Per Johan, Sanders, Rogier W., Zwick, Michael B., Wilson, Ian A., Ward, Andrew B.
Publicado no Nat Commun (2015)

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Por Julien, Jean-Philippe, Sok, Devin, Khayat, Reza, Lee, Jeong Hyun, Doores, Katie J., Walker, Laura M., Ramos, Alejandra, Diwanji, Devan C., Pejchal, Robert, Cupo, Albert, Katpally, Umesh, Depetris, Rafael S., Stanfield, Robyn L., McBride, Ryan, Marozsan, Andre J., Paulson, James C., Sanders, Rogier W., Moore, John P., Burton, Dennis R., Poignard, Pascal, Ward, Andrew B., Wilson, Ian A.
Publicado em 2013

A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans

Por Sok, Devin, Pauthner, Matthias, Briney, Bryan, Lee, Jeong Hyun, Saye-Francisco, Karen L., Hsueh, Jessica, Ramos, Alejandra, Le, Khoa M., Jones, Meaghan, Jardine, Joseph G., Bastidas, Raiza, Sarkar, Anita, Liang, Chi-Hui, Shivatare, Sachin S., Wu, Chung-Yi, Schief, William R., Wong, Chi-Huey, Wilson, Ian A., Ward, Andrew B., Zhu, Jiang, Poignard, Pascal, Burton, Dennis R.
Publicado no Immunity (2016)

Broad neutralization coverage of HIV by multiple highly potent antibodies

Por Walker, Laura M., Huber, Michael, Doores, Katie J., Falkowska, Emilia, Pejchal, Robert, Julien, Jean-Philippe, Wang, Sheng-Kai, Ramos, Alejandra, Chan-Hui, Po-Ying, Moyle, Matthew, Mitcham, Jennifer L., Hammond, Phillip W., Olsen, Ole A., Phung, Pham, Fling, Steven, Wong, Chi-Huey, Phogat, Sanjay, Wrin, Terri, Simek, Melissa D., Koff, Wayne C., Wilson, Ian A., Burton, Dennis R., Poignard, Pascal
Publicado em 2011

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

Por Landais, Elise, Huang, Xiayu, Havenar-Daughton, Colin, Murrell, Ben, Price, Matt A., Wickramasinghe, Lalinda, Ramos, Alejandra, Bian, Charoan B., Simek, Melissa, Allen, Susan, Karita, Etienne, Kilembe, William, Lakhi, Shabir, Inambao, Mubiana, Kamali, Anatoli, Sanders, Eduard J., Anzala, Omu, Edward, Vinodh, Bekker, Linda-Gail, Tang, Jianming, Gilmour, Jill, Kosakovsky-Pond, Sergei L., Phung, Pham, Wrin, Terri, Crotty, Shane, Godzik, Adam, Poignard, Pascal
Publicado no PLoS Pathog (2016)

A gp41 MPER-specific Llama VHH Requires a Hydrophobic CDR3 for Neutralization but not for Antigen Recognition

Por Lutje Hulsik, David, Liu, Ying-ying, Strokappe, Nika M., Battella, Simone, El Khattabi, Mohamed, McCoy, Laura E., Sabin, Charles, Hinz, Andreas, Hock, Miriam, Macheboeuf, Pauline, Bonvin, Alexandre M. J. J., Langedijk, Johannes P. M., Davis, David, Forsman Quigley, Anna, Aasa-Chapman, Marlén M. I., Seaman, Michael S., Ramos, Alejandra, Poignard, Pascal, Favier, Adrien, Simorre, Jean-Pierre, Weiss, Robin A., Verrips, C. Theo, Weissenhorn, Winfried, Rutten, Lucy
Publicado em 2013

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

Por Briney, Bryan, Sok, Devin, Jardine, Joseph G., Kulp, Daniel W., Skog, Patrick, Menis, Sergey, Jacak, Ronald, Kalyuzhniy, Oleksandr, de Val, Natalia, Sesterhenn, Fabian, Le, Khoa M., Ramos, Alejandra, Jones, Meaghan, Saye-Francisco, Karen L., Blane, Tanya R., Spencer, Skye, Georgeson, Erik, Hu, Xiaozhen, Ozorowski, Gabriel, Adachi, Yumiko, Kubitz, Michael, Sarkar, Anita, Wilson, Ian A., Ward, Andrew B., Nemazee, David, Burton, Dennis R., Schief, William R.
Publicado no Cell (2016)

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies

Por Sok, Devin, Laserson, Uri, Laserson, Jonathan, Liu, Yi, Vigneault, Francois, Julien, Jean-Philippe, Briney, Bryan, Ramos, Alejandra, Saye, Karen F., Le, Khoa, Mahan, Alison, Wang, Shenshen, Kardar, Mehran, Yaari, Gur, Walker, Laura M., Simen, Birgitte B., St. John, Elizabeth P., Chan-Hui, Po-Ying, Swiderek, Kristine, Kleinstein, Stephen H., Alter, Galit, Seaman, Michael S., Chakraborty, Arup K., Koller, Daphne, Wilson, Ian A., Church, George M., Burton, Dennis R., Poignard, Pascal
Publicado em 2013

Correction: The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies

Por Sok, Devin, Laserson, Uri, Laserson, Jonathan, Liu, Yi, Vigneault, Francois, Julien, Jean-Philippe, Briney, Bryan, Ramos, Alejandra, Saye, Karen F., Le, Khoa, Mahan, Alison, Wang, Shenshen, Kardar, Mehran, Yaari, Gur, Walker, Laura M., Simen, Birgitte B., St. John, Elizabeth P., Chan-Hui, Po-Ying, Swiderek, Kristine, Kleinstein, Stephen H., Alter, Galit, Seaman, Michael S., Chakraborty, Arup K., Koller, Daphne, Wilson, Ian A., Church, George M., Burton, Dennis R., Poignard, Pascal
Publicado em 2013

A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield

Por Pejchal, Robert, Doores, Katie J., Walker, Laura M., Khayat, Reza, Huang, Po-Ssu, Wang, Sheng-Kai, Stanfield, Robyn L., Julien, Jean-Philippe, Ramos, Alejandra, Crispin, Max, Depetris, Rafael, Katpally, Umesh, Marozsan, Andre, Cupo, Albert, Maloveste, Sebastien, Liu, Yan, McBride, Ryan, Ito, Yukishige, Sanders, Rogier W., Ogohara, Cassandra, Paulson, James C., Feizi, Ten, Scanlan, Christopher N., Wong, Chi-Huey, Moore, John P., Olson, William C., Ward, Andrew B., Poignard, Pascal, Schief, William R., Burton, Dennis R., Wilson, Ian A.
Publicado em 2011

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the pre-fusion conformation of the gp41 protein on cleaved Envelope trimers

Por Falkowska, Emilia, Le, Khoa M., Ramos, Alejandra, Doores, Katie J., Lee, Jeong Hyun, Blattner, Claudia, Ramirez, Alejandro, Derking, Ronald, van Gils, Marit J., Liang, Chi-Hui, Mcbride, Ryan, von Bredow, Benjamin, Shivatare, Sachin S., Wu, Chung-Yi, Chan-Hui, Po-Ying, Liu, Yan, Feizi, Ten, Zwick, Michael B., Koff, Wayne C., Seaman, Michael S., Swiderek, Kristine, Moore, John P., Evans, David, Paulson, James C., Wong, Chi-Huey, Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Poignard, Pascal, Burton, Dennis R.
Publicado em 2014