Conserved Changes in Envelope Function during Human Immunodeficiency Virus Type 1 Coreceptor Switching

We studied the evolution of human immunodeficiency virus type 1 (HIV-1) envelope function during the process of coreceptor switching from CCR5 to CXCR4. Site-directed mutagenesis was used to introduce most of the possible intermediate mutations in the envelope for four distinct coreceptor switch mut...

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Detalhes bibliográficos
Main Authors: Pastore, Cristina, Nedellec, Rebecca, Ramos, Alejandra, Hartley, Oliver, Miamidian, John L., Reeves, Jacqueline D., Mosier, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951319/
https://ncbi.nlm.nih.gov/pubmed/17507486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02792-06
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