High-Sequence Diversity and Rapid Virus Turnover Contribute to Higher Rates of Coreceptor Switching in Treatment-Experienced Subjects with HIV-1 Viremia

Coreceptor switching from CCR5 to CXCR4 is common during chronic HIV-1 infection, but is even more common in individuals who have failed antiretroviral therapy (ART). Prior studies have suggested rapid mutation and/or recombination of HIV-1 envelope (env) genes during coreceptor switching. We compar...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:AIDS Res Hum Retroviruses
Autori principali: Nedellec, Rebecca, Herbeck, Joshua T., Hunt, Peter W., Deeks, Steven G., Mullins, James I., Anton, Elizabeth D., Reeves, Jacqueline D., Mosier, Donald E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2017
Soggetti:
Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333564/
https://ncbi.nlm.nih.gov/pubmed/27604829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2016.0153
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi