Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding

Por He, Linling, Sok, Devin, Azadnia, Parisa, Hsueh, Jessica, Landais, Elise, Simek, Melissa, Koff, Wayne C., Poignard, Pascal, Burton, Dennis R., Zhu, Jiang
Publicado no Sci Rep (2014)

A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals

Por Walker, Laura M., Simek, Melissa D., Priddy, Frances, Gach, Johannes S., Wagner, Denise, Zwick, Michael B., Phogat, Sanjay K., Poignard, Pascal, Burton, Dennis R.
Publicado em 2010

Somatic Populations of PGT135–137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

Por Zhu, Jiang, O’Dell, Sijy, Ofek, Gilad, Pancera, Marie, Wu, Xueling, Zhang, Baoshan, Zhang, Zhenhai, Mullikin, James C., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.
Publicado em 2012

Virus-driven Inflammation Is Associated With the Development of bNAbs in Spontaneous Controllers of HIV

Por Dugast, Anne-Sophie, Arnold, Kelly, Lofano, Giuseppe, Moore, Sarah, Hoffner, Michelle, Simek, Melissa, Poignard, Pascal, Seaman, Michael, Suscovich, Todd J., Pereyra, Florencia, Walker, Bruce D., Lauffenburger, Doug, Kwon, Douglas S., Keele, Brandon F., Alter, Galit
Publicado no Clin Infect Dis (2017)

Rapid development of glycan-specific, broad, and potent anti–HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

Por Walker, Laura M., Sok, Devin, Nishimura, Yoshiaki, Donau, Olivia, Sadjadpour, Reza, Gautam, Rajeev, Shingai, Masashi, Pejchal, Robert, Ramos, Alejandra, Simek, Melissa D., Geng, Yu, Wilson, Ian A., Poignard, Pascal, Martin, Malcolm A., Burton, Dennis R.
Publicado em 2011

Conformational Epitope-Specific Broadly Neutralizing Plasma Antibodies Obtained from an HIV-1 Clade C-Infected Elite Neutralizer Mediate Autologous Virus Escape through Mutations i...

Por Patil, Shilpa, Kumar, Rajesh, Deshpande, Suprit, Samal, Sweety, Shrivastava, Tripti, Boliar, Saikat, Bansal, Manish, Chaudhary, Nakul Kumar, Srikrishnan, Aylur K., Murugavel, Kailapuri G., Solomon, Suniti, Simek, Melissa, Koff, Wayne C., Goyal, Rajat, Chakrabarti, Bimal K., Bhattacharya, Jayanta
Publicado no J Virol (2016)

Identification of an HIV-1 Clade A Envelope That Exhibits Broad Antigenicity and Neutralization Sensitivity and Elicits Antibodies Targeting Three Distinct Epitopes

Por Hoffenberg, Simon, Powell, Rebecca, Carpov, Alexei, Wagner, Denise, Wilson, Aaron, Kosakovsky Pond, Sergei, Lindsay, Ross, Arendt, Heather, DeStefano, Joanne, Phogat, Sanjay, Poignard, Pascal, Fling, Steven P., Simek, Melissa, LaBranche, Celia, Montefiori, David, Wrin, Terri, Phung, Pham, Burton, Dennis, Koff, Wayne, King, C. Richter, Parks, Christopher L., Caulfield, Michael J.
Publicado em 2013

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

Por Walker, Laura M., Phogat, Sanjay K., Chan-Hui, Po-Ying, Wagner, Denise, Phung, Pham, Goss, Julie L., Wrin, Terri, Simek, Melissa D., Fling, Steven, Mitcham, Jennifer L., Lehrman, Jennifer K., Priddy, Frances H., Olsen, Ole A., Frey, Steven M., Hammond, Phillip W., Kaminsky, Stephen, Zamb, Timothy, Moyle, Matthew, Koff, Wayne C., Poignard, Pascal, Burton, Dennis R.
Publicado em 2009

Broad neutralization coverage of HIV by multiple highly potent antibodies

Por Walker, Laura M., Huber, Michael, Doores, Katie J., Falkowska, Emilia, Pejchal, Robert, Julien, Jean-Philippe, Wang, Sheng-Kai, Ramos, Alejandra, Chan-Hui, Po-Ying, Moyle, Matthew, Mitcham, Jennifer L., Hammond, Phillip W., Olsen, Ole A., Phung, Pham, Fling, Steven, Wong, Chi-Huey, Phogat, Sanjay, Wrin, Terri, Simek, Melissa D., Koff, Wayne C., Wilson, Ian A., Burton, Dennis R., Poignard, Pascal
Publicado em 2011

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

Por Landais, Elise, Huang, Xiayu, Havenar-Daughton, Colin, Murrell, Ben, Price, Matt A., Wickramasinghe, Lalinda, Ramos, Alejandra, Bian, Charoan B., Simek, Melissa, Allen, Susan, Karita, Etienne, Kilembe, William, Lakhi, Shabir, Inambao, Mubiana, Kamali, Anatoli, Sanders, Eduard J., Anzala, Omu, Edward, Vinodh, Bekker, Linda-Gail, Tang, Jianming, Gilmour, Jill, Kosakovsky-Pond, Sergei L., Phung, Pham, Wrin, Terri, Crotty, Shane, Godzik, Adam, Poignard, Pascal
Publicado no PLoS Pathog (2016)

Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together...

Por Simek, Melissa D., Rida, Wasima, Priddy, Frances H., Pung, Pham, Carrow, Emily, Laufer, Dagna S., Lehrman, Jennifer K., Boaz, Mark, Tarragona-Fiol, Tony, Miiro, George, Birungi, Josephine, Pozniak, Anton, McPhee, Dale A., Manigart, Olivier, Karita, Etienne, Inwoley, André, Jaoko, Walter, DeHovitz, Jack, Bekker, Linda-Gail, Pitisuttithum, Punnee, Paris, Robert, Walker, Laura M., Poignard, Pascal, Wrin, Terri, Fast, Patricia E., Burton, Dennis R., Koff, Wayne C.
Publicado em 2009

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

Por Wu, Xueling, Zhou, Tongqing, Zhu, Jiang, Zhang, Baoshan, Georgiev, Ivelin, Wang, Charlene, Chen, Xuejun, Longo, Nancy S., Louder, Mark, McKee, Krisha, O’Dell, Sijy, Perfetto, Stephen, Schmidt, Stephen D., Shi, Wei, Wu, Lan, Yang, Yongping, Yang, Zhi-Yong, Yang, Zhongjia, Zhang, Zhenhai, Bonsignori, Mattia, Crump, John A., Kapiga, Saidi H., Sam, Noel E., Haynes, Barton F., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Doria-Rose, Nicole A., Connors, Mark, Mullikin, James C., Nabel, Gary J., Roederer, Mario, Shapiro, Lawrence, Kwong, Peter D., Mascola, John R.
Publicado em 2011

Multi-donor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for Effective HIV-1 Neutralization by VRCO1-class Antibodies

Por Zhou, Tongqing, Zhu, Jiang, Wu, Xueling, Moquin, Stephanie, Zhang, Baoshan, Acharya, Priyamvada, Georgiev, Ivelin S., Altae-Tran, Han R., Chuang, Gwo-Yu, Joyce, M. Gordon, Kwon, Young Do, Longo, Nancy S., Louder, Mark K., Luongo, Timothy, McKee, Krisha, Schramm, Chaim A., Skinner, Jeff, Yang, Yongping, Yang, Zhongjia, Zhang, Zhenhai, Zheng, Anqi, Bonsignori, Mattia, Haynes, Barton F., Scheid, Johannes F., Nussenzweig, Michel C., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Mullikin, James C., Connors, Mark, Shapiro, Lawrence, Nabel, Gary J., Mascola, John R., Kwong, Peter D.
Publicado em 2013

Mining the antibodyome for HIV-1–neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains

Por Zhu, Jiang, Ofek, Gilad, Yang, Yongping, Zhang, Baoshan, Louder, Mark K., Lu, Gabriel, McKee, Krisha, Pancera, Marie, Skinner, Jeff, Zhang, Zhenhai, Parks, Robert, Eudailey, Joshua, Lloyd, Krissey E., Blinn, Julie, Alam, S. Munir, Haynes, Barton F., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Mullikin, James C., Mascola, John R., Shapiro, Lawrence, Kwong, Peter D., Becker, Jesse, Benjamin, Betty, Blakesley, Robert, Bouffard, Gerry, Brooks, Shelise, Coleman, Holly, Dekhtyar, Mila, Gregory, Michael, Guan, Xiaobin, Gupta, Jyoti, Han, Joel, Hargrove, April, Ho, Shi-ling, Johnson, Taccara, Legaspi, Richelle, Lovett, Sean, Maduro, Quino, Masiello, Cathy, Maskeri, Baishali, McDowell, Jenny, Montemayor, Casandra, Mullikin, James, Park, Morgan, Riebow, Nancy, Schandler, Karen, Schmidt, Brian, Sison, Christina, Stantripop, Mal, Thomas, James, Thomas, Pam, Vemulapalli, Meg, Young, Alice
Publicado em 2013