HTJoinSolver: Human immunoglobulin VDJ partitioning using approximate dynamic programming constrained by conserved motifs

Por Russ, Daniel E, Ho, Kwan-Yuet, Longo, Nancy S
Publicado no BMC Bioinformatics (2015)

Characterization of immunoglobulin mutations in humans with activation-induced cytidine deaminase deficiency

Por Longo, Nancy S, Satorius, Colleen, Durandy, Anne, Lipsky, Peter E
Publicado em 2007

Specific In Vivo Deletion of B-Cell Subpopulations Expressing Human Immunoglobulins by the B-Cell Superantigen Protein L

Por Viau, Muriel, Longo, Nancy S., Lipsky, Peter E., Björck, Lars, Zouali, Moncef
Publicado em 2004

Therapeutic impact of the ethyl acetate extract of Tripterygium wilfordii Hook F on nephritis in NZB/W F1 mice

Por Tao, Xuelian, Fan, Fred, Hoffmann, Victoria, Longo, Nancy S, Lipsky, Peter E
Publicado em 2006

Lck Domains Differentially Contribute to Pre–T Cell Receptor (Tcr)–And TCR-α/β–Regulated Developmental Transitions

Por Lin, Kui, Longo, Nancy S., Wang, Xin, Hewitt, Judy A., Abraham, Kristin M.
Publicado em 2000

Characterization of immunoglobulin gene somatic hypermutation in the absence of activation-induced cytidine deaminase

Por Longo, Nancy S., Satorius, Colleen L., Plebani, Alessandro, Durandy, Anne, Lipsky, Peter E.
Publicado em 2008

An AICDA-independent mechanism of secondary VH gene rearrangement in preimmune human B cells Running title: Secondary rearrangement in human B cells

Por Longo, Nancy S., Grundy, Gabrielle J., Lee, Jisoo, Gellert, Martin, Lipsky, Peter E.
Publicado em 2008

Comparison of Antibody Repertoires Produced by HIV-1 Infection, Other Chronic and Acute Infections, and Systemic Autoimmune Disease

Por Breden, Felix, Lepik, Christa, Longo, Nancy S., Montero, Marinieve, Lipsky, Peter E., Scott, Jamie K.
Publicado em 2011

Effective Therapy for Nephritis in (NZB X NZW)F(1) Mice With Triptolide and Tripdiolide, the Principal Active Components of the Chinese Herbal Remedy Tripterygium wilfordii Hook F

Por Tao, Xuelian, Fan, Fred, Hoffmann, Victoria, Gao, Chun Y., Longo, Nancy S., Zerfas, Patricia, Lipsky, Peter E.
Publicado em 2008

Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of va...

Por Xiao, Xiaodong, Chen, Weizao, Feng, Yang, Zhu, Zhongyu, Prabakaran, Ponraj, Wang, Yanping, Zhang, Mei-Yun, Longo, Nancy S., Dimitrov, Dimiter S.
Publicado em 2009

Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting

Por Longo, Nancy S., Lugar, Patricia L., Yavuz, Sule, Zhang, Wen, Krijger, Peter H. L., Russ, Daniel E., Jima, Dereje D., Dave, Sandeep S., Grammer, Amrie C., Lipsky, Peter E.
Publicado em 2009

Isolation of human monoclonal antibodies from peripheral blood B cells

Por Huang, Jinghe, Doria-Rose, Nicole A, Longo, Nancy S, Laub, Leo, Lin, Chien-Li, Turk, Ellen, Kang, Byong H, Migueles, Stephen A, Bailer, Robert T, Mascola, John R, Connors, Mark
Publicado no Nat Protoc (2013)

Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding

Por Longo, Nancy S., Sutton, Matthew S., Shiakolas, Andrea R., Guenaga, Javier, Jarosinski, Marissa C., Georgiev, Ivelin S., McKee, Krisha, Bailer, Robert T., Louder, Mark K., O'Dell, Sijy, Connors, Mark, Wyatt, Richard T., Mascola, John R., Doria-Rose, Nicole A.
Publicado no J Virol (2016)

HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins

Por Li, Yuxing, O'Dell, Sijy, Wilson, Richard, Wu, Xueling, Schmidt, Stephen D., Hogerkorp, Carl-Magnus, Louder, Mark K., Longo, Nancy S., Poulsen, Christian, Guenaga, Javier, Chakrabarti, Bimal K., Doria-Rose, Nicole, Roederer, Mario, Connors, Mark, Mascola, John R., Wyatt, Richard T.
Publicado em 2012

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

Por Soto, Cinque, Ofek, Gilad, Joyce, M. Gordon, Zhang, Baoshan, McKee, Krisha, Longo, Nancy S., Yang, Yongping, Huang, Jinghe, Parks, Robert, Eudailey, Joshua, Lloyd, Krissey E., Alam, S. Munir, Haynes, Barton F., Mullikin, James C., Connors, Mark, Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.
Publicado no PLoS One (2016)

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

Por Huang, Jinghe, Ofek, Gilad, Laub, Leo, Louder, Mark K., Doria-Rose, Nicole A., Longo, Nancy S., Imamichi, Hiromi, Bailer, Robert T., Chakrabarti, Bimal, Sharma, Shailendra K., Alam, S. Munir, Wang, Tao, Yang, Yongping, Zhang, Baoshan, Migueles, Stephen A., Wyatt, Richard, Haynes, Barton F., Kwong, Peter D., Mascola, John R., Connors, Mark
Publicado no Nature (2012)

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

Por Wu, Xueling, Yang, Zhi-Yong, Li, Yuxing, Hogerkorp, Carl-Magnus, Schief, William R., Seaman, Michael S., Zhou, Tongqing, Schmidt, Stephen D., Wu, Lan, Xu, Ling, Longo, Nancy S., McKee, Krisha, O'Dell, Sijy, Louder, Mark K., Wycuff, Diane L., Feng, Yu, Nason, Martha, Doria-Rose, Nicole, Connors, Mark, Kwong, Peter D., Roederer, Mario, Wyatt, Richard T., Nabel, Gary J., Mascola, John R.
Publicado em 2010

Maturation and diversity of the VRC01-antibody lineage over 15 years of chronic HIV-1 infection

Por Wu, Xueling, Zhang, Zhenhai, Schramm, Chaim A., Joyce, M. Gordon, Do Kwon, Young, Zhou, Tongqing, Sheng, Zizhang, Zhang, Baoshan, O'Dell, Sijy, McKee, Krisha, Georgiev, Ivelin S., Chuang, Gwo-Yu, Longo, Nancy S., Lynch, Rebecca M., Saunders, Kevin O., Soto, Cinque, Srivatsan, Sanjay, Yang, Yongping, Bailer, Robert T., Louder, Mark K., Mullikin, James C., Connors, Mark, Kwong, Peter D., Mascola, John R., Shapiro, Lawrence
Publicado no Cell (2015)

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

Por Wu, Xueling, Zhou, Tongqing, Zhu, Jiang, Zhang, Baoshan, Georgiev, Ivelin, Wang, Charlene, Chen, Xuejun, Longo, Nancy S., Louder, Mark, McKee, Krisha, O’Dell, Sijy, Perfetto, Stephen, Schmidt, Stephen D., Shi, Wei, Wu, Lan, Yang, Yongping, Yang, Zhi-Yong, Yang, Zhongjia, Zhang, Zhenhai, Bonsignori, Mattia, Crump, John A., Kapiga, Saidi H., Sam, Noel E., Haynes, Barton F., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Doria-Rose, Nicole A., Connors, Mark, Mullikin, James C., Nabel, Gary J., Roederer, Mario, Shapiro, Lawrence, Kwong, Peter D., Mascola, John R.
Publicado em 2011

Multi-donor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for Effective HIV-1 Neutralization by VRCO1-class Antibodies

Por Zhou, Tongqing, Zhu, Jiang, Wu, Xueling, Moquin, Stephanie, Zhang, Baoshan, Acharya, Priyamvada, Georgiev, Ivelin S., Altae-Tran, Han R., Chuang, Gwo-Yu, Joyce, M. Gordon, Kwon, Young Do, Longo, Nancy S., Louder, Mark K., Luongo, Timothy, McKee, Krisha, Schramm, Chaim A., Skinner, Jeff, Yang, Yongping, Yang, Zhongjia, Zhang, Zhenhai, Zheng, Anqi, Bonsignori, Mattia, Haynes, Barton F., Scheid, Johannes F., Nussenzweig, Michel C., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Mullikin, James C., Connors, Mark, Shapiro, Lawrence, Nabel, Gary J., Mascola, John R., Kwong, Peter D.
Publicado em 2013