Where does amantadine bind to the influenza virus M2 proton channel?

Por Kozakov, Dima, Chuang, Gwo-Yu, Beglov, Dmitri, Vajda, Sandor
Publicado em 2010

NEP: web server for epitope prediction based on antibody neutralization of viral strains with diverse sequences

Por Chuang, Gwo-Yu, Liou, David, Kwong, Peter D., Georgiev, Ivelin S.
Publicado em 2014

DARS (Decoys As the Reference State) Potentials for Protein-Protein Docking

Por Chuang, Gwo-Yu, Kozakov, Dima, Brenke, Ryan, Comeau, Stephen R., Vajda, Sandor
Publicado em 2008

Binding Hot Spots and Amantadine Orientation in the Influenza A Virus M2 Proton Channel

Por Chuang, Gwo-Yu, Kozakov, Dima, Brenke, Ryan, Beglov, Dmitri, Guarnieri, Frank, Vajda, Sandor
Publicado em 2009

Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques

Por Brenke, Ryan, Kozakov, Dima, Chuang, Gwo-Yu, Beglov, Dmitri, Hall, David, Landon, Melissa R., Mattos, Carla, Vajda, Sandor
Publicado em 2009

Domain motion and interdomain hot spots in a multidomain enzyme

Por Chuang, Gwo-Yu, Mehra-Chaudhary, Ritcha, Ngan, Chi-Ho, Zerbe, Brandon S, Kozakov, Dima, Vajda, Sandor, Beamer, Lesa J
Publicado em 2010

Computational prediction of N-linked glycosylation incorporating structural properties and patterns

Por Chuang, Gwo-Yu, Boyington, Jeffrey C., Joyce, M. Gordon, Zhu, Jiang, Nabel, Gary J., Kwong, Peter D., Georgiev, Ivelin
Publicado em 2012

Application of asymmetric statistical potentials to antibody–protein docking

Por Brenke, Ryan, Hall, David R., Chuang, Gwo-Yu, Comeau, Stephen R., Bohnuud, Tanggis, Beglov, Dmitri, Schueler-Furman, Ora, Vajda, Sandor, Kozakov, Dima
Publicado em 2012

Structural conservation of druggable hot spots in protein–protein interfaces

Por Kozakov, Dima, Hall, David R., Chuang, Gwo-Yu, Cencic, Regina, Brenke, Ryan, Grove, Laurie E., Beglov, Dmitri, Pelletier, Jerry, Whitty, Adrian, Vajda, Sandor
Publicado em 2011

Structural Basis for Norovirus Inhibition and Fucose Mimicry by Citrate

Por Hansman, Grant S., Shahzad-ul-Hussan, Syed, McLellan, Jason S., Chuang, Gwo-Yu, Georgiev, Ivelin, Shimoike, Takashi, Katayama, Kazuhiko, Bewley, Carole A., Kwong, Peter D.
Publicado em 2012

Antibodyomics: bioinformatics technologies for understanding B‐cell immunity to HIV‐1

Por Kwong, Peter D., Chuang, Gwo‐Yu, DeKosky, Brandon J., Gindin, Tatyana, Georgiev, Ivelin S., Lemmin, Thomas, Schramm, Chaim A., Sheng, Zizhang, Soto, Cinque, Yang, An‐Suei, Mascola, John R., Shapiro, Lawrence
Publicado no Immunol Rev (2017)

Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6

Por Ofek, Gilad, Zirkle, Brett, Yang, Yongping, Zhu, Zhongyu, McKee, Krisha, Zhang, Baoshan, Chuang, Gwo-Yu, Georgiev, Ivelin S., O'Dell, Sijy, Doria-Rose, Nicole, Mascola, John R., Dimitrov, Dimiter S., Kwong, Peter D.
Publicado em 2014

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: Application to DJ-1 and Glucocerebrosidase

Por Landon, Melissa R., Lieberman, Raquel L., Hoang, Quyen Q., Ju, Shulin, Caaveiro, Jose M. M., Orwig, Susan D., Kozakov, Dima, Brenke, Ryan, Chuang, Gwo-Yu, Beglov, Dmitry, Vajda, Sandor, Petsko, Gregory A., Ringe, Dagmar
Publicado em 2009

Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with immunoglobulin-framework regions substantially reverted to germline

Por Georgiev, Ivelin S., Rudicell, Rebecca S., Saunders, Kevin O., Shi, Wei, Kirys, Tatsiana, McKee, Krisha, O'Dell, Sijy, Chuang, Gwo-Yu, Yang, Zhi-Yong, Ofek, Gilad, Connors, Mark, Mascola, John R., Nabel, Gary J., Kwong, Peter D.
Publicado em 2014

Residue-Level Prediction of HIV-1 Antibody Epitopes Based on Neutralization of Diverse Viral Strains

Por Chuang, Gwo-Yu, Acharya, Priyamvada, Schmidt, Stephen D., Yang, Yongping, Louder, Mark K., Zhou, Tongqing, Kwon, Young Do, Pancera, Marie, Bailer, Robert T., Doria-Rose, Nicole A., Nussenzweig, Michel C., Mascola, John R., Kwong, Peter D., Georgiev, Ivelin S.
Publicado em 2013

A Short Segment of the HIV-1 gp120 V1/V2 Region Is a Major Determinant of Resistance to V1/V2 Neutralizing Antibodies

Por Doria-Rose, Nicole A., Georgiev, Ivelin, O'Dell, Sijy, Chuang, Gwo-Yu, Staupe, Ryan P., McLellan, Jason S., Gorman, Jason, Pancera, Marie, Bonsignori, Mattia, Haynes, Barton F., Burton, Dennis R., Koff, Wayne C., Kwong, Peter D., Mascola, John R.
Publicado em 2012

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

Por Stewart-Jones, Guillaume B. E., Thomas, Paul V., Chen, Man, Druz, Aliaksandr, Joyce, M. Gordon, Kong, Wing-Pui, Sastry, Mallika, Soto, Cinque, Yang, Yongping, Zhang, Baoshan, Chen, Lei, Chuang, Gwo-Yu, Georgiev, Ivelin S., McLellan, Jason S., Srivatsan, Sanjay, Zhou, Tongqing, Baxa, Ulrich, Mascola, John R., Graham, Barney S., Kwong, Peter D.
Publicado no PLoS One (2015)

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

Por Chuang, Gwo-Yu, Geng, Hui, Pancera, Marie, Xu, Kai, Cheng, Cheng, Acharya, Priyamvada, Chambers, Michael, Druz, Aliaksandr, Tsybovsky, Yaroslav, Wanninger, Timothy G., Yang, Yongping, Doria-Rose, Nicole A., Georgiev, Ivelin S., Gorman, Jason, Joyce, M. Gordon, O'Dell, Sijy, Zhou, Tongqing, McDermott, Adrian B., Mascola, John R., Kwong, Peter D.
Publicado no J Virol (2017)

Eliminating antibody polyreactivity through addition of N-linked glycosylation

Por Chuang, Gwo-Yu, Zhang, Baoshan, McKee, Krisha, O'Dell, Sijy, Kwon, Young Do, Zhou, Tongqing, Blinn, Julie, Lloyd, Krissey, Parks, Robert, Von Holle, Tarra, Ko, Sung-Youl, Kong, Wing-Pui, Pegu, Amarendra, Wang, Keyun, Baruah, Kavitha, Crispin, Max, Mascola, John R, Moody, M Anthony, Haynes, Barton F, Georgiev, Ivelin S, Kwong, Peter D
Publicado no Protein Sci (2015)

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env

Por Georgiev, Ivelin S., Joyce, M. Gordon, Yang, Yongping, Sastry, Mallika, Zhang, Baoshan, Baxa, Ulrich, Chen, Rita E., Druz, Aliaksandr, Lees, Christopher R., Narpala, Sandeep, Schön, Arne, Van Galen, Joseph, Chuang, Gwo-Yu, Gorman, Jason, Harned, Adam, Pancera, Marie, Stewart-Jones, Guillaume B. E., Cheng, Cheng, Freire, Ernesto, McDermott, Adrian B., Mascola, John R., Kwong, Peter D.
Publicado no J Virol (2015)