The propagation of binding interactions to remote sites in proteins: Analysis of the binding of the monoclonal antibody D1.3 to lysozyme

بواسطة Freire, Ernesto
منشور في 1999

Can allosteric regulation be predicted from structure?

بواسطة Freire, Ernesto
منشور في 2000

Do Enthalpy and Entropy Distinguish First in Class From Best in Class?

بواسطة Freire, Ernesto
منشور في 2008

A Thermodynamic Approach to the Affinity Optimization of Drug Candidates

بواسطة Freire, Ernesto
منشور في 2009

Finding a better path to drug selectivity

بواسطة Kawasaki, Yuko, Freire, Ernesto
منشور في 2011

Three Easy Pieces

بواسطة Schön, Arne, Freire, Ernesto
الحاوية / القاعدة Biochim Biophys Acta (2015)

Enthalpy Screen of Drug Candidates

بواسطة Schön, Arne, Freire, Ernesto
الحاوية / القاعدة Anal Biochem (2016)

Long Range Cooperative Interactions Modulate Dimerization in SARS 3CL(pro)

بواسطة Barrila, Jennifer, Bacha, Usman, Freire, Ernesto
منشور في 2006

Naturally Occurring Variability in the Envelope Glycoprotein of HIV-1 and the Development of Cell Entry Inhibitors

بواسطة Brower, Evan T., Schön, Arne, Freire, Ernesto
منشور في 2010

Optimization of CD4/gp120 Inhibitors by Thermodynamic Guided Alanine Scanning Mutagenesis

بواسطة Liu, Yingyun, Schön, Arne, Freire, Ernesto
منشور في 2013

Thermodynamics-based drug design: strategies for inhibiting protein–protein interactions

بواسطة Schön, Arne, Lam, Sonia Y, Freire, Ernesto
منشور في 2011

Conformational stability and self-association equilibrium in biologics

بواسطة Clarkson, Benjamin R., Schön, Arne, Freire, Ernesto
الحاوية / القاعدة Drug Discov Today (2015)

Synthesis and biochemical evaluation of triazole/tetrazole-containing sulfonamides against thrombin and related serine proteases

بواسطة Siles, Rogelio, Kawasaki, Yuko, Ross, Patrick, Freire, Ernesto
منشور في 2011

Overcoming drug resistance in HIV-1 chemotherapy: The binding thermodynamics of Amprenavir and TMC-126 to wild-type and drug-resistant mutants of the HIV-1 protease

بواسطة Ohtaka, Hiroyasu, Velázquez-Campoy, Adrian, Xie, Dong, Freire, Ernesto
منشور في 2002

The flavodoxin from Helicobacter pylori: Structural Determinants of Thermostability and FMN Cofactor Binding

بواسطة Cremades, Nunilo, Velazquez-Campoy, Adrián, Freire, Ernesto, Sancho, Javier
منشور في 2007

The Binding Thermodynamics of the N-terminal Peptide of the CCR5 Coreceptor to HIV-1 Envelope Glycoprotein gp120

بواسطة Brower, Evan T., Schön, Arne, Klein, Jeffrey C., Freire, Ernesto
منشور في 2009

Temperature stability of proteins: Analysis of irreversible denaturation using isothermal calorimetry

بواسطة Schön, Arne, Clarkson, Benjamin R, Jaime, Maria, Freire, Ernesto
الحاوية / القاعدة Proteins (2017)

The structural distribution of cooperative interactions in proteins: Analysis of the native state ensemble

بواسطة Hilser, Vincent J., Dowdy, David, Oas, Terrence G., Freire, Ernesto
منشور في 1998

Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes

بواسطة Velazquez-Campoy, Adrian, Todd, Matthew J., Vega, Sonia, Freire, Ernesto
منشور في 2001

Chemical denaturation as a tool in the formulation optimization of biologics

بواسطة Freire, Ernesto, Schön, Arne, Hutchins, Burleigh M., Brown, Richard K.
منشور في 2013