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Conformational stability and self-association equilibrium in biologics
Biologics exist in equilibrium between native, partially denatured, and denatured conformational states. The population of any of these states is dictated by their Gibbs energy and can be altered by changes in physical and solution conditions. Some conformations have a tendency to self-associate and...
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| 出版年: | Drug Discov Today |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761488/ https://ncbi.nlm.nih.gov/pubmed/26608889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2015.11.007 |
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