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The Binding Thermodynamics of the N-terminal Peptide of the CCR5 Coreceptor to HIV-1 Envelope Glycoprotein gp120

The initial events of HIV-1 cell infection involve the sequential binding of the viral envelope glycoprotein gp120 to the cellular CD4 receptor and the coreceptor, usually CCR5 or CXCR4. Binding to the coreceptor triggers the chain of events that culminates with the entry of the virus into the cell....

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Detalhes bibliográficos
Main Authors: Brower, Evan T., Schön, Arne, Klein, Jeffrey C., Freire, Ernesto
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700308/
https://ncbi.nlm.nih.gov/pubmed/19170639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8021476
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