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The Binding Thermodynamics of the N-terminal Peptide of the CCR5 Coreceptor to HIV-1 Envelope Glycoprotein gp120

The initial events of HIV-1 cell infection involve the sequential binding of the viral envelope glycoprotein gp120 to the cellular CD4 receptor and the coreceptor, usually CCR5 or CXCR4. Binding to the coreceptor triggers the chain of events that culminates with the entry of the virus into the cell....

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Main Authors: Brower, Evan T., Schön, Arne, Klein, Jeffrey C., Freire, Ernesto
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700308/
https://ncbi.nlm.nih.gov/pubmed/19170639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8021476
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