gp120 envelope glycoproteins of human immunodeficiency viruses competitively antagonize signaling by coreceptors CXCR4 and CCR5

Signal transductions by the dual-function CXCR4 and CCR5 chemokine receptors/HIV type 1 (HIV-1) coreceptors were electrophysiologically monitored in Xenopus laevis oocytes that also coexpressed the viral receptor CD4 and a G protein-coupled inward-rectifying K(+) channel (Kir 3.1). Large Kir 3.1-dep...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Madani, Navid, Kozak, Susan L., Kavanaugh, Michael P., Kabat, David
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653130/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.8005
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