Cholesterol Influences Voltage-Gated Calcium Channels and BK-Type Potassium Channels in Auditory Hair Cells

por Purcell, Erin K., Liu, Liqian, Thomas, Paul V., Duncan, R. Keith
Publicado 2011

LOCALIZATION AND PROTEOMIC CHARACTERIZATION OF CHOLESTEROL-RICH MEMBRANE MICRODOMAINS IN THE INNER EAR

por Thomas, Paul V., Cheng, Andrew L., Colby, Candice C., Liu, Liqian, Patel, Chintan K., Josephs, Lydia, Duncan, R. Keith
Publicado en J Proteomics (2014)

Structural Basis of Mitochondrial Receptor Binding and Constriction by DRP1

por Kalia, Raghav, Wang, Ray Yu-Ruei, Yusuf, Ali, Thomas, Paul V., Agard, David A., Shaw, Janet M., Frost, Adam
Publicado en Nature (2018)

Hearing Loss and Hair Cell Death in Mice Given the Cholesterol-Chelating Agent Hydroxypropyl-β-Cyclodextrin

por Crumling, Mark A., Liu, Liqian, Thomas, Paul V., Benson, Jennifer, Kanicki, Ariane, Kabara, Lisa, Hälsey, Karin, Dolan, David, Duncan, R. Keith
Publicado 2012

Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus

por Boyington, Jeffrey C., Joyce, M. Gordon, Sastry, Mallika, Stewart-Jones, Guillaume B. E., Chen, Man, Kong, Wing-Pui, Ngwuta, Joan O., Thomas, Paul V., Tsybovsky, Yaroslav, Yang, Yongping, Zhang, Baoshan, Chen, Lei, Druz, Aliaksandr, Georgiev, Ivelin S., Ko, Kiyoon, Zhou, Tongqing, Mascola, John R., Graham, Barney S., Kwong, Peter D.
Publicado en PLoS One (2016)

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

por Stewart-Jones, Guillaume B. E., Thomas, Paul V., Chen, Man, Druz, Aliaksandr, Joyce, M. Gordon, Kong, Wing-Pui, Sastry, Mallika, Soto, Cinque, Yang, Yongping, Zhang, Baoshan, Chen, Lei, Chuang, Gwo-Yu, Georgiev, Ivelin S., McLellan, Jason S., Srivatsan, Sanjay, Zhou, Tongqing, Baxa, Ulrich, Mascola, John R., Graham, Barney S., Kwong, Peter D.
Publicado en PLoS One (2015)

Iterative structure-based improvement of a respiratory syncytial virus fusion glycoprotein vaccine

por Joyce, M. Gordon, Zhang, Baoshan, Ou, Li, Chen, Man, Chuang, Gwo-Yu, Druz, Aliaksandr, Kong, Wing-Pui, Lai, Yen-Ting, Rundlet, Emily J., Tsybovsky, Yaroslav, Yang, Yongping, Georgiev, Ivelin S., Guttman, Miklos, Lees, Christopher R., Pancera, Marie, Sastry, Mallika, Soto, Cinque, Stewart-Jones, Guillaume B.E., Thomas, Paul V., Van Galen, Joseph G., Baxa, Ulrich, Lee, Kelly K., Mascola, John R., Graham, Barney S., Kwong, Peter D.
Publicado en Nat Struct Mol Biol (2016)

Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1–4

por Stewart-Jones, Guillaume B. E., Chuang, Gwo-Yu, Xu, Kai, Zhou, Tongqing, Acharya, Priyamvada, Tsybovsky, Yaroslav, Ou, Li, Zhang, Baoshan, Fernandez-Rodriguez, Blanca, Gilardi, Valentina, Silacci-Fregni, Chiara, Beltramello, Martina, Baxa, Ulrich, Druz, Aliaksandr, Kong, Wing-Pui, Thomas, Paul V., Yang, Yongping, Foulds, Kathryn E., Todd, John-Paul, Wei, Hui, Salazar, Andres M., Scorpio, Diana G., Carragher, Bridget, Potter, Clinton S., Corti, Davide, Mascola, John R., Lanzavecchia, Antonio, Kwong, Peter D.
Publicado en Proc Natl Acad Sci U S A (2018)

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G

por Stewart-Jones, Guillaume B. E., Soto, Cinque, Lemmin, Thomas, Chuang, Gwo-Yu, Druz, Aliaksandr, Kong, Rui, Thomas, Paul V., Wagh, Kshitij, Zhou, Tongqing, Behrens, Anna-Janina, Bylund, Tatsiana, Choi, Chang W., Davison, Jack R., Georgiev, Ivelin S., Joyce, M. Gordon, Do Kwon, Young, Pancera, Marie, Taft, Justin, Yang, Yongping, Zhang, Baoshan, Shivatare, Sachin S., Shivatare, Vidya S., Lee, Chang-Chun D., Wu, Chung-Yi, Bewley, Carole A., Burton, Dennis R., Koff, Wayne C., Connors, Mark, Crispin, Max, Baxa, Ulrich, Korber, Bette T., Wong, Chi-Huey, Mascola, John R., Kwong, Peter D.
Publicado en Cell (2016)

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

por Lee, Jiwon, Boutz, Daniel R, Chromikova, Veronika, Joyce, M Gordon, Vollmers, Christopher, Leung, Kwanyee, Horton, Andrew P, DeKosky, Brandon J, Lee, Chang-Han, Lavinder, Jason J, Murrin, Ellen M, Chrysostomou, Constantine, Hoi, Kam Hon, Tsybovsky, Yaroslav, Thomas, Paul V, Druz, Aliaksandr, Zhang, Baoshan, Zhang, Yi, Wang, Lingshu, Kong, Wing-Pui, Park, Daechan, Popova, Lyubov I, Dekker, Cornelia L, Davis, Mark M, Carter, Chalise E, Ross, Ted M, Ellington, Andrew D, Wilson, Patrick C, Marcotte, Edward M, Mascola, John R, Ippolito, Gregory C, Krammer, Florian, Quake, Stephen R, Kwong, Peter D, Georgiou, George
Publicado en Nat Med (2016)

Vaccine-Induced Antibodies that Neutralize Group 1 and 2 Influenza A Viruses

por Joyce, M. Gordon, Wheatley, Adam K., Thomas, Paul V., Chuang, Gwo-Yu, Soto, Cinque, Bailer, Robert T., Druz, Aliaksandr, Georgiev, Ivelin S., Gillespie, Rebecca A., Kanekiyo, Masaru, Kong, Wing-Pui, Leung, Kwanyee, Narpala, Sandeep N., Prabhakaran, Madhu S., Yang, Eun Sung, Zhang, Baoshan, Zhang, Yi, Asokan, Mangaiarkarasi, Boyington, Jeffrey C., Bylund, Tatsiana, Darko, Sam, Lees, Christopher R., Ransier, Amy, Shen, Chen-Hsiang, Wang, Lingshu, Whittle, James R., Wu, Xueling, Yassine, Hadi M., Santos, Celia, Matsuoka, Yumiko, Tsybovsky, Yaroslav, Baxa, Ulrich, Mullikin, James C., Subbarao, Kanta, Douek, Daniel C., Graham, Barney S., Koup, Richard A., Ledgerwood, Julie E., Roederer, Mario, Shapiro, Lawrence, Kwong, Peter D., Mascola, John R., McDermott, Adrian B.
Publicado en Cell (2016)

Crystal structure, conformational fixation, and entry-related interactions of mature ligand-free HIV-1 Env

por Kwon, Young Do, Pancera, Marie, Acharya, Priyamvada, Georgiev, Ivelin S., Crooks, Emma T., Gorman, Jason, Joyce, M. Gordon, Guttman, Miklos, Ma, Xiaochu, Narpala, Sandeep, Soto, Cinque, Terry, Daniel S., Yang, Yongping, Zhou, Tongqing, Ahlsen, Goran, Bailer, Robert T., Chambers, Michael, Chuang, Gwo-Yu, Doria-Rose, Nicole A., Druz, Aliaksandr, Hallen, Mark A., Harned, Adam, Kirys, Tatsiana, Louder, Mark K., O’Dell, Sijy, Ofek, Gilad, Osawa, Keiko, Prabhakaran, Madhu, Sastry, Mallika, Stewart-Jones, Guillaume B.E., Stuckey, Jonathan, Thomas, Paul V., Tittley, Tishina, Williams, Constance, Zhang, Baoshan, Zhao, Hong, Zhou, Zhou, Donald, Bruce R., Lee, Lawrence K., Zolla-Pazner, Susan, Baxa, Ulrich, Schön, Arne, Freire, Ernesto, Shapiro, Lawrence, Lee, Kelly K., Arthos, James, Munro, James B., Blanchard, Scott C., Mothes, Walther, Binley, James M., McDermott, Adrian B., Mascola, John R., Kwong, Peter D.
Publicado en Nat Struct Mol Biol (2015)

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

por Joyce, M. Gordon, Chen, Wei-Hung, Sankhala, Rajeshwer S., Hajduczki, Agnes, Thomas, Paul V., Choe, Misook, Chang, William, Peterson, Caroline E., Martinez, Elizabeth, Morrison, Elaine B., Smith, Clayton, Ahmed, Aslaa, Wieczorek, Lindsay, Anderson, Alexander, Chen, Rita E., Case, James Brett, Li, Yifan, Oertel, Therese, Rosado, Lorean, Ganesh, Akshaya, Whalen, Connor, Carmen, Joshua M., Mendez-Rivera, Letzibeth, Karch, Christopher, Gohain, Neelakshi, Villar, Zuzana, McCurdy, David, Beck, Zoltan, Kim, Jiae, Shrivastava, Shikha, Jobe, Ousman, Dussupt, Vincent, Molnar, Sebastian, Tran, Ursula, Kannadka, Chandrika B., Zemil, Michelle, Khanh, Htet, Wu, Weimin, Cole, Matthew A., Duso, Debra K., Kummer, Larry W., Lang, Tricia J., Muncil, Shania E., Currier, Jeffrey R., Krebs, Shelly J., Polonis, Victoria R., Rajan, Saravanan, McTamney, Patrick M., Esser, Mark T., Reiley, William W., Rolland, Morgane, de Val, Natalia, Diamond, Michael S., Gromowski, Gregory D., Matyas, Gary R., Rao, Mangala, Michael, Nelson L., Modjarrad, Kayvon
Publicado en bioRxiv (2021)

A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters

por Wuertz, Kathryn McGuckin, Barkei, Erica K., Chen, Wei-Hung, Martinez, Elizabeth J., Lakhal-Naouar, Ines, Jagodzinski, Linda L., Paquin-Proulx, Dominic, Gromowski, Gregory D., Swafford, Isabella, Ganesh, Akshaya, Dong, Ming, Zeng, Xiankun, Thomas, Paul V., Sankhala, Rajeshwer S., Hajduczki, Agnes, Peterson, Caroline E., Kuklis, Caitlin, Soman, Sandrine, Wieczorek, Lindsay, Zemil, Michelle, Anderson, Alexander, Darden, Janice, Hernandez, Heather, Grove, Hannah, Dussupt, Vincent, Hack, Holly, de la Barrera, Rafael, Zarling, Stasya, Wood, James F., Froude, Jeffrey W., Gagne, Matthew, Henry, Amy R., Mokhtari, Elham Bayat, Mudvari, Prakriti, Krebs, Shelly J., Pekosz, Andrew S., Currier, Jeffrey R., Kar, Swagata, Porto, Maciel, Winn, Adrienne, Radzyminski, Kamil, Lewis, Mark G., Vasan, Sandhya, Suthar, Mehul, Polonis, Victoria R., Matyas, Gary R., Boritz, Eli A., Douek, Daniel C., Seder, Robert A., Daye, Sharon P., Rao, Mangala, Peel, Sheila A., Joyce, M. Gordon, Bolton, Diane L., Michael, Nelson L., Modjarrad, Kayvon
Publicado en bioRxiv (2021)

Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques

por King, Hannah A. D., Gordon Joyce, M., Naouar, Ines Elakhal, Ahmed, Aslaa, Cincotta, Camila Macedo, Subra, Caroline, Peachman, Kristina K., Hack, Holly H., Chen, Rita E., Thomas, Paul V., Chen, Wei-Hung, Sankhala, Rajeshwer S., Hajduczki, Agnes, Martinez, Elizabeth J., Peterson, Caroline E., Chang, William C., Choe, Misook, Smith, Clayton, Headley, Jarrett A., Elyard, Hanne A., Cook, Anthony, Anderson, Alexander, Wuertz, Kathryn McGuckin, Dong, Ming, Swafford, Isabella, Case, James B., Currier, Jeffrey R., Lal, Kerri G., Amare, Mihret F., Dussupt, Vincent, Molnar, Sebastian, Daye, Sharon P., Zeng, Xiankun, Barkei, Erica K., Alfson, Kendra, Staples, Hilary M., Carrion, Ricardo, Krebs, Shelly J., Paquin-Proulx, Dominic, Karasavvas, Nicos, Polonis, Victoria R., Jagodzinski, Linda L., Vasan, Sandhya, Scott, Paul T., Huang, Yaoxing, Nair, Manoj S., Ho, David D., de Val, Natalia, Diamond, Michael S., Lewis, Mark G., Rao, Mangala, Matyas, Gary R., Gromowski, Gregory D., Peel, Sheila A., Michael, Nelson L., Modjarrad, Kayvon, Bolton, Diane L.
Publicado en bioRxiv (2021)

Efficacy of a Broadly Neutralizing SARS-CoV-2 Ferritin Nanoparticle Vaccine in Nonhuman Primates

por Joyce, Michael G., King, Hannah A. D., Naouar, Ines Elakhal, Ahmed, Aslaa, Peachman, Kristina K., Cincotta, Camila Macedo, Subra, Caroline, Chen, Rita E., Thomas, Paul V., Chen, Wei-Hung, Sankhala, Rajeshwer S., Hajduczki, Agnes, Martinez, Elizabeth J., Peterson, Caroline E., Chang, William C., Choe, Misook, Smith, Clayton, Lee, Parker J., Headley, Jarrett A., Taddese, Mekdi G., Elyard, Hanne A., Cook, Anthony, Anderson, Alexander, McGuckin-Wuertz, Kathryn, Dong, Ming, Swafford, Isabella, Case, James B., Currier, Jeffrey R., Lal, Kerri G., O’Connell, Robert J., Molnar, Sebastian, Nair, Manoj S., Dussupt, Vincent, Daye, Sharon P., Zeng, Xiankun, Barkei, Erica K., Staples, Hilary M., Alfson, Kendra, Carrion, Ricardo, Krebs, Shelly J., Paquin-Proulx, Dominic, Karasavva, Nicos, Polonis, Victoria R., Jagodzinski, Linda L., Amare, Mihret F., Vasan, Sandhya, Scott, Paul T., Huang, Yaoxing, Ho, David D., de Val, Natalia, Diamond, Michael S., Lewis, Mark G., Rao, Mangala, Matyas, Gary R., Gromowski, Gregory D., Peel, Sheila A., Michael, Nelson L., Bolton, Diane L., Modjarrad, Kayvon
Publicado en bioRxiv (2021)

Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance

por Mavor, David, Barlow, Kyle A., Asarnow, Daniel, Birman, Yuliya, Britain, Derek, Chen, Weilin, Green, Evan M., Kenner, Lillian R., Mensa, Bruk, Morinishi, Leanna S., Nelson, Charlotte A., Poss, Erin M., Suresh, Pooja, Tian, Ruilin, Arhar, Taylor, Ary, Beatrice E., Bauer, David P., Bergman, Ian D., Brunetti, Rachel M., Chio, Cynthia M., Dai, Shizhong A., Dickinson, Miles S., Elledge, Susanna K., Helsell, Cole V. M., Hendel, Nathan L., Kang, Emily, Kern, Nadja, Khoroshkin, Matvei S., Kirkemo, Lisa L., Lewis, Greyson R., Lou, Kevin, Marin, Wesley M., Maxwell, Alison M., McTigue, Peter F., Myers-Turnbull, Douglas, Nagy, Tamas L., Natale, Andrew M., Oltion, Keely, Pourmal, Sergei, Reder, Gabriel K., Rettko, Nicholas J., Rohweder, Peter J., Schwarz, Daniel M. C, Tan, Sophia K., Thomas, Paul V., Tibble, Ryan W., Town, Jason P., Tsai, Mary K., Ugur, Fatima S., Wassarman, Douglas R., Wolff, Alexander M., Wu, Taia S., Bogdanoff, Derek, Li, Jennifer, Thorn, Kurt S., O'Conchúir, Shane, Swaney, Danielle L., Chow, Eric D., Madhani, Hiten D., Redding, Sy, Bolon, Daniel N., Kortemme, Tanja, DeRisi, Joseph L., Kampmann, Martin, Fraser, James S.
Publicado en Biol Open (2018)

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

por Gordon, David E., Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V., Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S., Obernier, Kirsten, Guo, Jeffrey Z., Batra, Jyoti, Kaake, Robyn M., Weckstein, Andrew R., Owens, Tristan W., Gupta, Meghna, Pourmal, Sergei, Titus, Erron W., Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O’Meara, Matthew J., Tummino, Tia A., Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L., Fabius, Jacqueline M., Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M., Naing, Zun Zar Chi, Pulido, Ernst H., Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A., Azumaya, Caleigh M., Billesbølle, Christian, Brilot, Axel F., Campbell, Melody G., Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T., Liu, Yanxin, Merz, Gregory E., Moritz, Michelle, Nguyen, Henry C., Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Sun, Ming, Young, Iris D., Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R., Chen, Jen, Chio, Cynthia M., Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L., Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E., Melo, Arthur A., Moss, Frank R., Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K., Pospiech, Thomas H., Safari, Maliheh, Sangwan, Smriti, Schaefer, Kaitlin, Thomas, Paul V., Thwin, Aye C., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Whitis, Natalie, Yu, Zanlin, Zhang, Kaihua, Zhang, Yang, Zhou, Fengbo, Saltzberg, Daniel, Hodder, Anthony J., Shun-Shion, Amber S., Williams, Daniel M., White, Kris M., Rosales, Romel, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Patel, Arvind H., Rihn, Suzannah, Khalid, Mir M., Vallejo-Gracia, Albert, Fozouni, Parinaz, Simoneau, Camille R., Roth, Theodore L., Wu, David, Karim, Mohd Anisul, Ghoussaini, Maya, Dunham, Ian, Berardi, Francesco, Weigang, Sebastian, Chazal, Maxime, Park, Jisoo, Logue, James, McGrath, Marisa, Weston, Stuart, Haupt, Robert, Hastie, C. James, Elliott, Matthew, Brown, Fiona, Burness, Kerry A., Reid, Elaine, Dorward, Mark, Johnson, Clare, Wilkinson, Stuart G., Geyer, Anna, Giesel, Daniel M., Baillie, Carla, Raggett, Samantha, Leech, Hannah, Toth, Rachel, Goodman, Nicola, Keough, Kathleen C., Lind, Abigail L., Klesh, Reyna J., Hemphill, Kafi R., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Maures, Travis, Pollard, Katherine S., Sali, Andrej, Agard, David A., Cheng, Yifan, Fraser, James S., Frost, Adam, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M., Alessi, Dario R., Davies, Paul, Frieman, Matthew B., Ideker, Trey, Abate, Carmen, Jouvenet, Nolwenn, Kochs, Georg, Shoichet, Brian, Ott, Melanie, Palmarini, Massimo, Shokat, Kevan M., García-Sastre, Adolfo, Rassen, Jeremy A., Grosse, Robert, Rosenberg, Oren S., Verba, Kliment A., Basler, Christopher F., Vignuzzi, Marco, Peden, Andrew A., Beltrao, Pedro, Krogan, Nevan J.
Publicado en Science (2020)