Vaccine-Induced Antibodies that Neutralize Group 1 and 2 Influenza A Viruses

Antibodies capable of neutralizing divergent influenza A viruses could form the basis of a universal vaccine. Here, from subjects enrolled in an H5N1 DNA/MIV-prime-boost influenza vaccine trial, we sorted hemagglutinin-cross reactive memory-B cells and identified three antibody classes, each capable...

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Veröffentlicht in:Cell
Hauptverfasser: Joyce, M. Gordon, Wheatley, Adam K., Thomas, Paul V., Chuang, Gwo-Yu, Soto, Cinque, Bailer, Robert T., Druz, Aliaksandr, Georgiev, Ivelin S., Gillespie, Rebecca A., Kanekiyo, Masaru, Kong, Wing-Pui, Leung, Kwanyee, Narpala, Sandeep N., Prabhakaran, Madhu S., Yang, Eun Sung, Zhang, Baoshan, Zhang, Yi, Asokan, Mangaiarkarasi, Boyington, Jeffrey C., Bylund, Tatsiana, Darko, Sam, Lees, Christopher R., Ransier, Amy, Shen, Chen-Hsiang, Wang, Lingshu, Whittle, James R., Wu, Xueling, Yassine, Hadi M., Santos, Celia, Matsuoka, Yumiko, Tsybovsky, Yaroslav, Baxa, Ulrich, Mullikin, James C., Subbarao, Kanta, Douek, Daniel C., Graham, Barney S., Koup, Richard A., Ledgerwood, Julie E., Roederer, Mario, Shapiro, Lawrence, Kwong, Peter D., Mascola, John R., McDermott, Adrian B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978566/
https://ncbi.nlm.nih.gov/pubmed/27453470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.06.043
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