Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus

Respiratory syncytial virus (RSV) is a significant cause of severe respiratory illness worldwide, particularly in infants, young children, and the elderly. Although no licensed vaccine is currently available, an engineered version of the metastable RSV fusion (F) surface glycoprotein—stabilized in t...

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Foilsithe in:PLoS One
Main Authors: Boyington, Jeffrey C., Joyce, M. Gordon, Sastry, Mallika, Stewart-Jones, Guillaume B. E., Chen, Man, Kong, Wing-Pui, Ngwuta, Joan O., Thomas, Paul V., Tsybovsky, Yaroslav, Yang, Yongping, Zhang, Baoshan, Chen, Lei, Druz, Aliaksandr, Georgiev, Ivelin S., Ko, Kiyoon, Zhou, Tongqing, Mascola, John R., Graham, Barney S., Kwong, Peter D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963090/
https://ncbi.nlm.nih.gov/pubmed/27463224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159709
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