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Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus

Respiratory syncytial virus (RSV) is a significant cause of severe respiratory illness worldwide, particularly in infants, young children, and the elderly. Although no licensed vaccine is currently available, an engineered version of the metastable RSV fusion (F) surface glycoprotein—stabilized in t...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Boyington, Jeffrey C., Joyce, M. Gordon, Sastry, Mallika, Stewart-Jones, Guillaume B. E., Chen, Man, Kong, Wing-Pui, Ngwuta, Joan O., Thomas, Paul V., Tsybovsky, Yaroslav, Yang, Yongping, Zhang, Baoshan, Chen, Lei, Druz, Aliaksandr, Georgiev, Ivelin S., Ko, Kiyoon, Zhou, Tongqing, Mascola, John R., Graham, Barney S., Kwong, Peter D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963090/
https://ncbi.nlm.nih.gov/pubmed/27463224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159709
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