Dimerization-based Control of Cooperativity

Yazar: Bouhaddou, Mehdi, Birtwistle, Marc R.
Baskı/Yayın Bilgisi 2014

Integrating Transcriptomic Data with Mechanistic Systems Pharmacology Models for Virtual Drug Combination Trials

Yazar: Barrette, Anne Marie, Bouhaddou, Mehdi, Birtwistle, Marc R.
Yayımlandı ACS Chem Neurosci (2017)

Engineered mammalian RNAi can elicit antiviral protection that negates the requirement for the interferon response

Yazar: Benitez, Asiel Arturo, Spanko, Laura Adrienne, Bouhaddou, Mehdi, Sachs, David, tenOever, Benjamin Robert
Yayımlandı Cell Rep (2015)

Analysis of copy number loss of the ErbB4 receptor tyrosine kinase in glioblastoma

Yazar: Jones, DeAnalisa C., Scanteianu, Adriana, DiStefano, Matthew, Bouhaddou, Mehdi, Birtwistle, Marc R.
Yayımlandı PLoS One (2018)

Mapping the protein–protein and genetic interactions of cancer to guide precision medicine

Yazar: Bouhaddou, Mehdi, Eckhardt, Manon, Naing, Zun Zar Chi, Kim, Minkyu, Ideker, Trey, Krogan, Nevan J
Yayımlandı Curr Opin Genet Dev (2019)

The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2

Yazar: Tutuncuoglu, Beril, Cakir, Merve, Batra, Jyoti, Bouhaddou, Mehdi, Eckhardt, Manon, Gordon, David E., Krogan, Nevan J.
Yayımlandı Cancer Discov (2020)

Validating Antibodies for Quantitative Western Blot Measurements with Microwestern Array

Yazar: Koch, Rick J., Barrette, Anne Marie, Stern, Alan D., Hu, Bin, Bouhaddou, Mehdi, Azeloglu, Evren U., Iyengar, Ravi, Birtwistle, Marc R.
Yayımlandı Sci Rep (2018)

Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer

Yazar: Bouhaddou, Mehdi, Yu, Li J., Lunardi, Serena, Stamatelos, Spyros K., Mack, Fiona, Gallo, James M., Birtwistle, Marc R., Walz, Antje‐Christine
Yayımlandı Clin Transl Sci (2020)

Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses

Yazar: Wang, Ruofan, Simoneau, Camille R., Kulsuptrakul, Jessie, Bouhaddou, Mehdi, Travisano, Katherine, Hayashi, Jennifer M., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Krogan, Nevan J., Ott, Melanie, Puschnik, Andreas S.
Yayımlandı bioRxiv (2020)

A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens

Yazar: Bouhaddou, Mehdi, Barrette, Anne Marie, Stern, Alan D., Koch, Rick J., DiStefano, Matthew S., Riesel, Eric A., Santos, Luis C., Tan, Annie L., Mertz, Alex E., Birtwistle, Marc R.
Yayımlandı PLoS Comput Biol (2018)

Drug response consistency in CCLE and CGP

Yazar: Bouhaddou, Mehdi, DiStefano, Matthew S., Riesel, Eric A., Carrasco, Emilce, Holzapfel, Hadassa Y., Jones, DeAnalisa C., Smith, Gregory R., Stern, Alan D., Somani, Sulaiman S., Thompson, T. Victoria, Birtwistle, Marc R.
Yayımlandı Nature (2016)

Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses

Yazar: Wang, Ruofan, Simoneau, Camille R., Kulsuptrakul, Jessie, Bouhaddou, Mehdi, Travisano, Katherine A., Hayashi, Jennifer M., Carlson-Stevermer, Jared, Zengel, James R., Richards, Christopher M., Fozouni, Parinaz, Oki, Jennifer, Rodriguez, Lauren, Joehnk, Bastian, Walcott, Keith, Holden, Kevin, Sil, Anita, Carette, Jan E., Krogan, Nevan J., Ott, Melanie, Puschnik, Andreas S.
Yayımlandı Cell (2021)

A Comparison of mRNA Sequencing with Random Primed and 3′-Directed Libraries

Yazar: Xiong, Yuguang, Soumillon, Magali, Wu, Jie, Hansen, Jens, Hu, Bin, van Hasselt, Johan G. C., Jayaraman, Gomathi, Lim, Ryan, Bouhaddou, Mehdi, Ornelas, Loren, Bochicchio, Jim, Lenaeus, Lindsay, Stocksdale, Jennifer, Shim, Jaehee, Gomez, Emilda, Sareen, Dhruv, Svendsen, Clive, Thompson, Leslie M., Mahajan, Milind, Iyengar, Ravi, Sobie, Eric A., Azeloglu, Evren U., Birtwistle, Marc R.
Yayımlandı Sci Rep (2017)

Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

Yazar: Reuschl, Ann-Kathrin, Thorne, Lucy G., Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, Hiatt, Joseph, Soucheray, Margaret, Turner, Jane, Fabius, Jacqueline M., Nguyen, Gina T., Swaney, Danielle L., Rosales, Romel, White, Kris M., Avilés, Pablo, Kirby, Ilsa T., Melnyk, James E., Shi, Ying, Zhang, Ziyang, Shokat, Kevan M., García-Sastre, Adolfo, Jolly, Clare, Towers, Gregory J., Krogan, Nevan J.
Yayımlandı bioRxiv (2021)

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

Yazar: White, Kris M., Rosales, Romel, Yildiz, Soner, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Jangra, Sonia, Uccellini, Melissa B., Rathnasinghe, Raveen, Coughlan, Lynda, Martinez-Romero, Carles, Batra, Jyoti, Rojc, Ajda, Bouhaddou, Mehdi, Fabius, Jacqueline M., Obernier, Kirsten, Dejosez, Marion, Guillén, María José, Losada, Alejandro, Avilés, Pablo, Schotsaert, Michael, Zwaka, Thomas, Vignuzzi, Marco, Shokat, Kevan M., Krogan, Nevan J., García-Sastre, Adolfo
Yayımlandı Science (2021)

Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

Yazar: Thorne, Lucy G, Bouhaddou, Mehdi, Reuschl, Ann-Kathrin, Zuliani-Alvarez, Lorena, Polacco, Ben, Pelin, Adrian, Batra, Jyoti, Whelan, Matthew V.X., Ummadi, Manisha, Rojc, Ajda, Turner, Jane, Obernier, Kirsten, Braberg, Hannes, Soucheray, Margaret, Richards, Alicia, Chen, Kuei-Ho, Harjai, Bhavya, Memon, Danish, Hosmillo, Myra, Hiatt, Joseph, Jahun, Aminu, Goodfellow, Ian G., Fabius, Jacqueline M., Shokat, Kevan, Jura, Natalia, Verba, Klim, Noursadeghi, Mahdad, Beltrao, Pedro, Swaney, Danielle L., Garcia-Sastre, Adolfo, Jolly, Clare, Towers, Greg J., Krogan, Nevan J.
Yayımlandı bioRxiv (2021)

Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization

Yazar: Varona, José F., Landete, Pedro, Lopez-Martin, Jose A., Estrada, Vicente, Paredes, Roger, Guisado-Vasco, Pablo, de Orueta, Lucía Fernández, Torralba, Miguel, Fortún, Jesús, Vates, Roberto, Barberán, José, Clotet, Bonaventura, Ancochea, Julio, Carnevali, Daniel, Cabello, Noemí, Porras, Lourdes, Gijón, Paloma, Monereo, Alfonso, Abad, Daniel, Zúñiga, Sonia, Sola, Isabel, Rodon, Jordi, Izquierdo-Useros, Nuria, Fudio, Salvador, Pontes, María José, de Rivas, Beatriz, Girón de Velasco, Patricia, Sopesén, Belén, Nieto, Antonio, Gómez, Javier, Avilés, Pablo, Lubomirov, Rubin, White, Kris M., Rosales, Romel, Yildiz, Soner, Reuschl, Ann-Kathrin, Thorne, Lucy G., Jolly, Clare, Towers, Greg J., Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, Enjuanes, Luis, Fernández-Sousa, Jose M., Krogan, Nevan J., Jimeno, José M., García-Sastre, Adolfo
Yayımlandı medRxiv (2021)

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Yazar: Bouhaddou, Mehdi, Memon, Danish, Meyer, Bjoern, White, Kris M., Rezelj, Veronica V., Correa Marrero, Miguel, Polacco, Benjamin J., Melnyk, James E., Ulferts, Svenja, Kaake, Robyn M., Batra, Jyoti, Richards, Alicia L., Stevenson, Erica, Gordon, David E., Rojc, Ajda, Obernier, Kirsten, Fabius, Jacqueline M., Soucheray, Margaret, Miorin, Lisa, Moreno, Elena, Koh, Cassandra, Tran, Quang Dinh, Hardy, Alexandra, Robinot, Rémy, Vallet, Thomas, Nilsson-Payant, Benjamin E., Hernandez-Armenta, Claudia, Dunham, Alistair, Weigang, Sebastian, Knerr, Julian, Modak, Maya, Quintero, Diego, Zhou, Yuan, Dugourd, Aurelien, Valdeolivas, Alberto, Patil, Trupti, Li, Qiongyu, Hüttenhain, Ruth, Cakir, Merve, Muralidharan, Monita, Kim, Minkyu, Jang, Gwendolyn, Tutuncuoglu, Beril, Hiatt, Joseph, Guo, Jeffrey Z., Xu, Jiewei, Bouhaddou, Sophia, Mathy, Christopher J.P., Gaulton, Anna, Manners, Emma J., Félix, Eloy, Shi, Ying, Goff, Marisa, Lim, Jean K., McBride, Timothy, O’Neal, Michael C., Cai, Yiming, Chang, Jason C.J., Broadhurst, David J., Klippsten, Saker, De wit, Emmie, Leach, Andrew R., Kortemme, Tanja, Shoichet, Brian, Ott, Melanie, Saez-Rodriguez, Julio, tenOever, Benjamin R., Mullins, R. Dyche, Fischer, Elizabeth R., Kochs, Georg, Grosse, Robert, García-Sastre, Adolfo, Vignuzzi, Marco, Johnson, Jeffery R., Shokat, Kevan M., Swaney, Danielle L., Beltrao, Pedro, Krogan, Nevan J.
Yayımlandı Cell (2020)

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

Yazar: Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Yayımlandı bioRxiv (2021)

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

Yazar: Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Yayımlandı Res Sq (2021)