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Engineered mammalian RNAi can elicit antiviral protection that negates the requirement for the interferon response
While the intrinsic antiviral cell defenses of many kingdoms utilize pathogen-specific small RNAs, the antiviral response of chordates is primarily protein-based and not uniquely tailored to the incoming microbe. In an effort to explain this evolutionary bifurcation, we determined whether antiviral...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654977/ https://ncbi.nlm.nih.gov/pubmed/26549455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.020 |
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