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Mitogen-activated Protein Kinase-mediated Licensing of Interferon Regulatory Factor 3/7 Reinforces the Cell Response to Virus

The induction of the intrinsic antiviral defense in mammals relies on the accumulation of foreign genetic material. As such, complete engagement of this response is limited to replication-competent viruses. Interferon regulatory factors (IRFs) are mediators of this defense with shared enhancer eleme...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schmid, Sonja, Sachs, David, tenOever, Benjamin R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879553/
https://ncbi.nlm.nih.gov/pubmed/24275658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.519934
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