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A Versatile RNA Vector for Delivery of Coding and Noncoding RNAs

The discovery that RNA viruses, lacking any DNA intermediate, can be engineered to express both coding and noncoding RNAs suggests that this platform may have therapeutic value as a delivery vehicle. Here we illustrate that a self-replicating, noninfectious RNA, modeled on influenza virus, provides...

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Sonraí Bibleagrafaíochta
Main Authors: Schmid, Sonja, Zony, Lum C., tenOever, Benjamin R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911536/
https://ncbi.nlm.nih.gov/pubmed/24307584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03267-13
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