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A Versatile RNA Vector for Delivery of Coding and Noncoding RNAs
The discovery that RNA viruses, lacking any DNA intermediate, can be engineered to express both coding and noncoding RNAs suggests that this platform may have therapeutic value as a delivery vehicle. Here we illustrate that a self-replicating, noninfectious RNA, modeled on influenza virus, provides...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3911536/ https://ncbi.nlm.nih.gov/pubmed/24307584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03267-13 |
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